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APOEε4 associates with microglial activation independently of Aβ plaques and tau tangles.
Ferrari-Souza JP, Lussier FZ, Leffa DT, Therriault J, Tissot C, Bellaver B, Ferreira PCL, Malpetti M, Wang YT, Povala G, Benedet AL, Ashton NJ, Chamoun M, Servaes S, Bezgin G, Kang MS, Stevenson J, Rahmouni N, Pallen V, Poltronetti NM, O'Brien JT, Rowe JB, Cohen AD, Lopez OL, Tudorascu DL, Karikari TK, Klunk WE, Villemagne VL, Soucy JP, Gauthier S, Souza DO, Zetterberg H, Blennow K, Zimmer ER, Rosa-Neto P, Pascoal TA. Ferrari-Souza JP, et al. Among authors: leffa dt. Sci Adv. 2023 Apr 5;9(14):eade1474. doi: 10.1126/sciadv.ade1474. Epub 2023 Apr 5. Sci Adv. 2023. PMID: 37018391 Free PMC article.
Activated peripheral blood mononuclear cell mediators trigger astrocyte reactivity.
Bellaver B, Rocha AS, Souza DG, Leffa DT, De Bastiani MA, Schu G, Lukasewicz Ferreira PC, Venturin GT, Greggio S, Ribeiro CT, da Costa JC, Moreira JCF, Gelain DP, Torres ILDS, Klamt F, Zimmer ER. Bellaver B, et al. Among authors: leffa dt. Brain Behav Immun. 2019 Aug;80:879-888. doi: 10.1016/j.bbi.2019.05.041. Epub 2019 Jun 5. Brain Behav Immun. 2019. PMID: 31176000 Free article.
Astrocyte Biomarkers in Alzheimer Disease: A Systematic Review and Meta-analysis.
Bellaver B, Ferrari-Souza JP, Uglione da Ros L, Carter SF, Rodriguez-Vieitez E, Nordberg A, Pellerin L, Rosa-Neto P, Leffa DT, Zimmer ER. Bellaver B, et al. Among authors: leffa dt. Neurology. 2021 Jun 14;96(24):e2944-e2955. doi: 10.1212/WNL.0000000000012109. Neurology. 2021. PMID: 33952650
Antidepressant-Like Effects of Chronic Guanosine in the Olfactory Bulbectomy Mouse Model.
Almeida RF, Nonose Y, Ganzella M, Loureiro SO, Rocha A, Machado DG, Bellaver B, Fontella FU, Leffa DT, Pettenuzzo LF, Venturin GT, Greggio S, da Costa JC, Zimmer ER, Elisabetsky E, Souza DO. Almeida RF, et al. Among authors: leffa dt. Front Psychiatry. 2021 Aug 4;12:701408. doi: 10.3389/fpsyt.2021.701408. eCollection 2021. Front Psychiatry. 2021. PMID: 34421682 Free PMC article.
Astrocyte biomarker signatures of amyloid-β and tau pathologies in Alzheimer's disease.
Ferrari-Souza JP, Ferreira PCL, Bellaver B, Tissot C, Wang YT, Leffa DT, Brum WS, Benedet AL, Ashton NJ, De Bastiani MA, Rocha A, Therriault J, Lussier FZ, Chamoun M, Servaes S, Bezgin G, Kang MS, Stevenson J, Rahmouni N, Pallen V, Poltronetti NM, Klunk WE, Tudorascu DL, Cohen AD, Villemagne VL, Gauthier S, Blennow K, Zetterberg H, Souza DO, Karikari TK, Zimmer ER, Rosa-Neto P, Pascoal TA. Ferrari-Souza JP, et al. Among authors: leffa dt. Mol Psychiatry. 2022 Nov;27(11):4781-4789. doi: 10.1038/s41380-022-01716-2. Epub 2022 Aug 10. Mol Psychiatry. 2022. PMID: 35948658 Free PMC article.
The Association of Age-Related and Off-Target Retention with Longitudinal Quantification of [18F]MK6240 Tau PET in Target Regions.
Tissot C, Servaes S, Lussier FZ, Ferrari-Souza JP, Therriault J, Ferreira PCL, Bezgin G, Bellaver B, Leffa DT, Mathotaarachchi SS, Chamoun M, Stevenson J, Rahmouni N, Kang MS, Pallen V, Margherita-Poltronetti N, Wang YT, Fernandez-Arias J, Benedet AL, Zimmer ER, Soucy JP, Tudorascu DL, Cohen AD, Sharp M, Gauthier S, Massarweh G, Lopresti B, Klunk WE, Baker SL, Villemagne VL, Rosa-Neto P, Pascoal TA. Tissot C, et al. Among authors: leffa dt. J Nucl Med. 2023 Mar;64(3):452-459. doi: 10.2967/jnumed.122.264434. Epub 2022 Nov 17. J Nucl Med. 2023. PMID: 36396455 Free PMC article.
42 results