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The synthetic aminoglycoside ELX-02 induces readthrough of G550X-CFTR producing superfunctional protein that can be further enhanced by CFTR modulators.
Chen J, Thrasher K, Fu L, Wang W, Aghamohammadzadeh S, Wen H, Tang L, Keeling KM, Falk Libby E, Bedwell DM, Rowe SM. Chen J, et al. Among authors: wang w. Am J Physiol Lung Cell Mol Physiol. 2023 Jun 1;324(6):L756-L770. doi: 10.1152/ajplung.00038.2023. Epub 2023 Apr 4. Am J Physiol Lung Cell Mol Physiol. 2023. PMID: 37014818 Free PMC article.
Cystin is required for maintaining fibrocystin (FPC) levels and safeguarding proteome integrity in mouse renal epithelial cells: A mechanistic connection between the kidney defects in cpk mice and human ARPKD.
Zhang YJ, Yang C, Wang W, Harafuji N, Stasiak P, Bell PD, Caldovic L, Sztul E, Guay-Woodford LM, Bebok Z. Zhang YJ, et al. Among authors: wang w. FASEB J. 2023 Jul;37(7):e23008. doi: 10.1096/fj.202300100R. FASEB J. 2023. PMID: 37318790 Free PMC article.
Crosstalk between human immunodeficiency virus infection and salivary bacterial function in men who have sex with men.
Guo Y, Wang W, Yu Y, Sun X, Zhang B, Wang Y, Cao J, Wen S, Wang X, Li Y, Cai S, Wu R, Duan W, Xia W, Wei F, Duan J, Dong H, Guo S, Zhang F, Sun Z, Huang X. Guo Y, et al. Among authors: wang w. Front Cell Infect Microbiol. 2024 May 8;14:1341545. doi: 10.3389/fcimb.2024.1341545. eCollection 2024. Front Cell Infect Microbiol. 2024. PMID: 38779561 Free PMC article.
Pharmacogenomic analysis in adrenocortical carcinoma reveals genetic features associated with mitotane sensitivity and potential therapeutics.
Zhang J, Wu L, Su T, Liu H, Jiang L, Jiang Y, Wu Z, Chen L, Li H, Zheng J, Sun Y, Peng H, Han R, Ning G, Ye L, Wang W. Zhang J, et al. Among authors: wang w. Front Endocrinol (Lausanne). 2024 May 8;15:1365321. doi: 10.3389/fendo.2024.1365321. eCollection 2024. Front Endocrinol (Lausanne). 2024. PMID: 38779454 Free PMC article.
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