Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

122 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Results By Year timeline is not available.
Page 1
Expanding the Paradigm of Structure-Based Drug Design: Molecular Dynamics Simulations Support the Development of New Pyridine-Based Protein Kinase C-Targeted Agonists.
Lautala S, Provenzani R, Tarvainen I, Sirna K, Karhu ST, Grazhdankin E, Lehtinen AK, Sa'd H, Koivuniemi A, Xhaard H, Tuominen RK, Talman V, Bunker A, Yli-Kauhaluoma J. Lautala S, et al. Among authors: tuominen rk. J Med Chem. 2023 Apr 13;66(7):4588-4602. doi: 10.1021/acs.jmedchem.2c01448. Epub 2023 Apr 3. J Med Chem. 2023. PMID: 37010933 Free PMC article.
Scaffold hopping from (5-hydroxymethyl) isophthalates to multisubstituted pyrimidines diminishes binding affinity to the C1 domain of protein kinase C.
Provenzani R, Tarvainen I, Brandoli G, Lempinen A, Artes S, Turku A, Jäntti MH, Talman V, Yli-Kauhaluoma J, Tuominen RK, Boije Af Gennäs G. Provenzani R, et al. Among authors: tuominen rk. PLoS One. 2018 Apr 11;13(4):e0195668. doi: 10.1371/journal.pone.0195668. eCollection 2018. PLoS One. 2018. PMID: 29641588 Free PMC article.
Protein kinases as drug targets.
Yli-Kauhaluoma J, Tuominen RK. Yli-Kauhaluoma J, et al. Among authors: tuominen rk. Curr Top Med Chem. 2011;11(11):1304. doi: 10.2174/156802611795589557. Curr Top Med Chem. 2011. PMID: 21513501 No abstract available.
122 results