Wångsell F - Search Results

1

A3907, a systemic ASBT inhibitor, improves cholestasis in mice by multiorgan activity and shows translational relevance to humans.

Caballero-Camino FJ, Rodrigues PM, Wångsell F, Agirre-Lizaso A, Olaizola P, Izquierdo-Sanchez L, Perugorria MJ, Bujanda L, Angelin B, Straniero S, Wallebäck A, Starke I, Gillberg PG, Strängberg E, Bonn B, Mattsson JP, Madsen MR, Hansen HH, Lindström E, Åkerblad P, Banales JM. Caballero-Camino FJ, et al. Among authors: wangsell f. Hepatology. 2023 Sep 1;78(3):709-726. doi: 10.1097/HEP.0000000000000376. Epub 2023 Apr 1. Hepatology. 2023. PMID: 36999529 Free PMC article.

2

Radical Functionalization of Unsaturated Amino Acids: Synthesis of Side-Chain-Fluorinated, Azido-Substituted, and Hydroxylated Amino Acids.

Reeve PAP, Grabowska U, Oden LS, Wiktelius D, Wångsell F, Jackson RFW. Reeve PAP, et al. Among authors: wangsell f. ACS Omega. 2019 Jun 21;4(6):10854-10865. doi: 10.1021/acsomega.9b01509. eCollection 2019 Jun 30. ACS Omega. 2019. PMID: 31460183 Free PMC article.

3

Synthesis and labeling of a piperazine-based library of ¹¹C-labeled ligands for imaging of the vesicular acetylcholine transporter.

Bergman S, Estrada S, Hall H, Rahman R, Blomgren A, Larhed M, Svedberg M, Thibblin A, Wångsell F, Antoni G. Bergman S, et al. Among authors: wangsell f. J Labelled Comp Radiopharm. 2014 Jun 30;57(8):525-32. doi: 10.1002/jlcr.3208. Epub 2014 Jul 3. J Labelled Comp Radiopharm. 2014. PMID: 24991704

4

Use of a HEHEHE purification tag instead of a hexahistidine tag improves biodistribution of affibody molecules site-specifically labeled with (99m)Tc, (111)In, and (125)I.

Hofstrom C, Orlova A, Altai M, Wangsell F, Graslund T, Tolmachev V. Hofstrom C, et al. Among authors: wangsell f. J Med Chem. 2011 Jun 9;54(11):3817-26. doi: 10.1021/jm200065e. Epub 2011 May 12. J Med Chem. 2011. PMID: 21524142

5

Investigation of α-phenylnorstatine and α-benzylnorstatine as transition state isostere motifs in the search for new BACE-1 inhibitors.

Wångsell F, Nordeman P, Sävmarker J, Emanuelsson R, Jansson K, Lindberg J, Rosenquist S, Samuelsson B, Larhed M. Wångsell F, et al. Bioorg Med Chem. 2011 Jan 1;19(1):145-55. doi: 10.1016/j.bmc.2010.11.042. Epub 2010 Nov 26. Bioorg Med Chem. 2011. PMID: 21183353

6

Synthesis of potent BACE-1 inhibitors incorporating a hydroxyethylene isostere as central core.

Wångsell F, Gustafsson K, Kvarnström I, Borkakoti N, Edlund M, Jansson K, Lindberg J, Hallberg A, Rosenquist A, Samuelsson B. Wångsell F, et al. Eur J Med Chem. 2010 Mar;45(3):870-82. doi: 10.1016/j.ejmech.2009.11.013. Epub 2009 Nov 12. Eur J Med Chem. 2010. PMID: 20036448

7

Design and synthesis of BACE-1 inhibitors utilizing a tertiary hydroxyl motif as the transition state mimic.

Wångsell F, Russo F, Sävmarker J, Rosenquist A, Samuelsson B, Larhed M. Wångsell F, et al. Bioorg Med Chem Lett. 2009 Aug 15;19(16):4711-4. doi: 10.1016/j.bmcl.2009.06.065. Epub 2009 Jun 21. Bioorg Med Chem Lett. 2009. PMID: 19576765

8

Novel potent macrocyclic inhibitors of the hepatitis C virus NS3 protease: use of cyclopentane and cyclopentene P2-motifs.

Bäck M, Johansson PO, Wångsell F, Thorstensson F, Kvarnström I, Ayesa S, Wähling H, Pelcman M, Jansson K, Lindström S, Wallberg H, Classon B, Rydergård C, Vrang L, Hamelink E, Hallberg A, Rosenquist S, Samuelsson B. Bäck M, et al. Among authors: wangsell f. Bioorg Med Chem. 2007 Nov 15;15(22):7184-202. doi: 10.1016/j.bmc.2007.07.027. Epub 2007 Aug 22. Bioorg Med Chem. 2007. PMID: 17845856

9

Synthesis of novel potent hepatitis C virus NS3 protease inhibitors: discovery of 4-hydroxy-cyclopent-2-ene-1,2-dicarboxylic acid as a N-acyl-L-hydroxyproline bioisostere.

Thorstensson F, Wångsell F, Kvarnström I, Vrang L, Hamelink E, Jansson K, Hallberg A, Rosenquist S, Samuelsson B. Thorstensson F, et al. Among authors: wangsell f. Bioorg Med Chem. 2007 Jan 15;15(2):827-38. doi: 10.1016/j.bmc.2006.10.044. Epub 2006 Oct 25. Bioorg Med Chem. 2007. PMID: 17107807

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