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N-Acylthiadiazolines, a new class of liver X receptor agonists with selectivity for LXRbeta.
Molteni V, Li X, Nabakka J, Liang F, Wityak J, Koder A, Vargas L, Romeo R, Mitro N, Mak PA, Seidel HM, Haslam JA, Chow D, Tuntland T, Spalding TA, Brock A, Bradley M, Castrillo A, Tontonoz P, Saez E. Molteni V, et al. Among authors: mitro n. J Med Chem. 2007 Aug 23;50(17):4255-9. doi: 10.1021/jm070453f. Epub 2007 Aug 1. J Med Chem. 2007. PMID: 17665897
Myeloid apolipoprotein E controls dendritic cell antigen presentation and T cell activation.
Bonacina F, Coe D, Wang G, Longhi MP, Baragetti A, Moregola A, Garlaschelli K, Uboldi P, Pellegatta F, Grigore L, Da Dalt L, Annoni A, Gregori S, Xiao Q, Caruso D, Mitro N, Catapano AL, Marelli-Berg FM, Norata GD. Bonacina F, et al. Among authors: mitro n. Nat Commun. 2018 Aug 6;9(1):3083. doi: 10.1038/s41467-018-05322-1. Nat Commun. 2018. PMID: 30082772 Free PMC article.
The nuclear receptor LXR is a glucose sensor.
Mitro N, Mak PA, Vargas L, Godio C, Hampton E, Molteni V, Kreusch A, Saez E. Mitro N, et al. Nature. 2007 Jan 11;445(7124):219-23. doi: 10.1038/nature05449. Epub 2006 Dec 24. Nature. 2007. PMID: 17187055
Dissection of the insulin-sensitizing effect of liver X receptor ligands.
Commerford SR, Vargas L, Dorfman SE, Mitro N, Rocheford EC, Mak PA, Li X, Kennedy P, Mullarkey TL, Saez E. Commerford SR, et al. Among authors: mitro n. Mol Endocrinol. 2007 Dec;21(12):3002-12. doi: 10.1210/me.2007-0156. Epub 2007 Aug 23. Mol Endocrinol. 2007. PMID: 17717069
145 results