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Unique pharmacodynamic properties and low abuse liability of the μ-opioid receptor ligand (S)-methadone.
Michaelides M, Levinstein M, De Oliveira P, Casajuana-Martin N, Quiroz C, Budinich R, Rais R, Rea W, Ventriglia E, Llopart N, Casadó-Anguera V, Moreno E, Walther D, Glatfelter G, Weinshenker D, Zarate C, Casado V, Baumann M, Pardo L, Ferre S. Michaelides M, et al. Among authors: casado v. Res Sq [Preprint]. 2023 Mar 23:rs.3.rs-2644719. doi: 10.21203/rs.3.rs-2644719/v1. Res Sq. 2023. PMID: 36993715 Free PMC article. Updated. Preprint.
Dimer-based model for heptaspanning membrane receptors.
Franco R, Casadó V, Mallol J, Ferré S, Fuxe K, Cortés A, Ciruela F, Lluis C, Canela EI. Franco R, et al. Among authors: casado v. Trends Biochem Sci. 2005 Jul;30(7):360-6. doi: 10.1016/j.tibs.2005.05.010. Trends Biochem Sci. 2005. PMID: 15951182
Novel pharmacological targets based on receptor heteromers.
Franco R, Casadó V, Cortés A, Pérez-Capote K, Mallol J, Canela E, Ferré S, Lluis C. Franco R, et al. Among authors: casado v. Brain Res Rev. 2008 Aug;58(2):475-82. doi: 10.1016/j.brainresrev.2008.06.002. Epub 2008 Jun 20. Brain Res Rev. 2008. PMID: 18620000 Review.
Interactions between intracellular domains as key determinants of the quaternary structure and function of receptor heteromers.
Navarro G, Ferré S, Cordomi A, Moreno E, Mallol J, Casadó V, Cortés A, Hoffmann H, Ortiz J, Canela EI, Lluís C, Pardo L, Franco R, Woods AS. Navarro G, et al. Among authors: casado v. J Biol Chem. 2010 Aug 27;285(35):27346-27359. doi: 10.1074/jbc.M110.115634. Epub 2010 Jun 18. J Biol Chem. 2010. PMID: 20562103 Free PMC article.
G protein-coupled receptor heteromers as new targets for drug development.
Ferré S, Navarro G, Casadó V, Cortés A, Mallol J, Canela EI, Lluís C, Franco R. Ferré S, et al. Among authors: casado v. Prog Mol Biol Transl Sci. 2010;91:41-52. doi: 10.1016/S1877-1173(10)91002-8. Prog Mol Biol Transl Sci. 2010. PMID: 20691958 Free PMC article. Review.
Direct involvement of sigma-1 receptors in the dopamine D1 receptor-mediated effects of cocaine.
Navarro G, Moreno E, Aymerich M, Marcellino D, McCormick PJ, Mallol J, Cortés A, Casadó V, Canela EI, Ortiz J, Fuxe K, Lluís C, Ferré S, Franco R. Navarro G, et al. Among authors: casado v. Proc Natl Acad Sci U S A. 2010 Oct 26;107(43):18676-81. doi: 10.1073/pnas.1008911107. Epub 2010 Oct 18. Proc Natl Acad Sci U S A. 2010. PMID: 20956312 Free PMC article.
Dopamine D1-histamine H3 receptor heteromers provide a selective link to MAPK signaling in GABAergic neurons of the direct striatal pathway.
Moreno E, Hoffmann H, Gonzalez-Sepúlveda M, Navarro G, Casadó V, Cortés A, Mallol J, Vignes M, McCormick PJ, Canela EI, Lluís C, Moratalla R, Ferré S, Ortiz J, Franco R. Moreno E, et al. Among authors: casado v. J Biol Chem. 2011 Feb 18;286(7):5846-54. doi: 10.1074/jbc.M110.161489. Epub 2010 Dec 20. J Biol Chem. 2011. PMID: 21173143 Free PMC article.
Striatal pre- and postsynaptic profile of adenosine A(2A) receptor antagonists.
Orru M, Bakešová J, Brugarolas M, Quiroz C, Beaumont V, Goldberg SR, Lluís C, Cortés A, Franco R, Casadó V, Canela EI, Ferré S. Orru M, et al. Among authors: casado v. PLoS One. 2011 Jan 11;6(1):e16088. doi: 10.1371/journal.pone.0016088. PLoS One. 2011. PMID: 21264319 Free PMC article.
206 results