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Tuft cell-derived acetylcholine regulates epithelial fluid secretion.
Billipp TE, Fung C, Webeck LM, Sargent DB, Gologorsky MB, McDaniel MM, Kasal DN, McGinty JW, Barrow KA, Rich LM, Barilli A, Sabat M, Debley JS, Myers R, Howitt MR, von Moltke J. Billipp TE, et al. Among authors: mcginty jw. bioRxiv [Preprint]. 2023 Mar 22:2023.03.17.533208. doi: 10.1101/2023.03.17.533208. bioRxiv. 2023. PMID: 36993541 Free PMC article. Updated. Preprint.
Tuft cell-derived acetylcholine promotes epithelial chloride secretion and intestinal helminth clearance.
Billipp TE, Fung C, Webeck LM, Sargent DB, Gologorsky MB, Chen Z, McDaniel MM, Kasal DN, McGinty JW, Barrow KA, Rich LM, Barilli A, Sabat M, Debley JS, Wu C, Myers R, Howitt MR, von Moltke J. Billipp TE, et al. Among authors: mcginty jw. Immunity. 2024 May 6:S1074-7613(24)00144-4. doi: 10.1016/j.immuni.2024.03.023. Online ahead of print. Immunity. 2024. PMID: 38744291
PGD2 and CRTH2 counteract Type 2 cytokine-elicited intestinal epithelial responses during helminth infection.
Oyesola OO, Shanahan MT, Kanke M, Mooney BM, Webb LM, Smita S, Matheson MK, Campioli P, Pham D, Früh SP, McGinty JW, Churchill MJ, Cahoon JL, Sundaravaradan P, Flitter BA, Mouli K, Nadjsombati MS, Kamynina E, Peng SA, Cubitt RL, Gronert K, Lord JD, Rauch I, von Moltke J, Sethupathy P, Tait Wojno ED. Oyesola OO, et al. Among authors: mcginty jw. J Exp Med. 2021 Sep 6;218(9):e20202178. doi: 10.1084/jem.20202178. Epub 2021 Jul 20. J Exp Med. 2021. PMID: 34283207 Free PMC article.
Discriminative T cell recognition of cross-reactive islet-antigens is associated with HLA-DQ8 transdimer-mediated autoimmune diabetes.
Chow IT, Gates TJ, Papadopoulos GK, Moustakas AK, Kolawole EM, Notturno RJ, McGinty JW, Torres-Chinn N, James EA, Greenbaum C, Nepom GT, Evavold BD, Kwok WW. Chow IT, et al. Among authors: mcginty jw. Sci Adv. 2019 Aug 21;5(8):eaaw9336. doi: 10.1126/sciadv.aaw9336. eCollection 2019 Aug. Sci Adv. 2019. PMID: 31457096 Free PMC article.
Detection of Succinate by Intestinal Tuft Cells Triggers a Type 2 Innate Immune Circuit.
Nadjsombati MS, McGinty JW, Lyons-Cohen MR, Jaffe JB, DiPeso L, Schneider C, Miller CN, Pollack JL, Nagana Gowda GA, Fontana MF, Erle DJ, Anderson MS, Locksley RM, Raftery D, von Moltke J. Nadjsombati MS, et al. Among authors: mcginty jw. Immunity. 2018 Jul 17;49(1):33-41.e7. doi: 10.1016/j.immuni.2018.06.016. Immunity. 2018. PMID: 30021144 Free PMC article.
Modifying Enzymes Are Elicited by ER Stress, Generating Epitopes That Are Selectively Recognized by CD4+ T Cells in Patients With Type 1 Diabetes.
Marre ML, McGinty JW, Chow IT, DeNicola ME, Beck NW, Kent SC, Powers AC, Bottino R, Harlan DM, Greenbaum CJ, Kwok WW, Piganelli JD, James EA. Marre ML, et al. Among authors: mcginty jw. Diabetes. 2018 Jul;67(7):1356-1368. doi: 10.2337/db17-1166. Epub 2018 Apr 13. Diabetes. 2018. PMID: 29654212 Free PMC article.
Combinatorial detection of autoreactive CD8+ T cells with HLA-A2 multimers: a multi-centre study by the Immunology of Diabetes Society T Cell Workshop.
James EA, Abreu JRF, McGinty JW, Odegard JM, Fillié YE, Hocter CN, Culina S, Ladell K, Price DA, Alkanani A, Rihanek M, Fitzgerald-Miller L, Skowera A, Speake C, Gottlieb P, Davidson HW, Wong FS, Roep B, Mallone R; Immunology of Diabetes Society T Cell Workshop Committee. James EA, et al. Among authors: mcginty jw. Diabetologia. 2018 Mar;61(3):658-670. doi: 10.1007/s00125-017-4508-8. Epub 2017 Dec 1. Diabetologia. 2018. PMID: 29196783
15 results