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Tuft cell-derived acetylcholine regulates epithelial fluid secretion.
Billipp TE, Fung C, Webeck LM, Sargent DB, Gologorsky MB, McDaniel MM, Kasal DN, McGinty JW, Barrow KA, Rich LM, Barilli A, Sabat M, Debley JS, Myers R, Howitt MR, von Moltke J. Billipp TE, et al. Among authors: howitt mr. bioRxiv [Preprint]. 2023 Mar 22:2023.03.17.533208. doi: 10.1101/2023.03.17.533208. bioRxiv. 2023. PMID: 36993541 Free PMC article. Updated. Preprint.
Tuft cells mediate commensal remodeling of the small intestinal antimicrobial landscape.
Fung C, Fraser LM, Barrón GM, Gologorsky MB, Atkinson SN, Gerrick ER, Hayward M, Ziegelbauer J, Li JA, Nico KF, Tyner MDW, DeSchepper LB, Pan A, Salzman NH, Howitt MR. Fung C, et al. Among authors: howitt mr. Proc Natl Acad Sci U S A. 2023 Jun 6;120(23):e2216908120. doi: 10.1073/pnas.2216908120. Epub 2023 May 30. Proc Natl Acad Sci U S A. 2023. PMID: 37253002 Free PMC article.
Tuft cell-derived acetylcholine promotes epithelial chloride secretion and intestinal helminth clearance.
Billipp TE, Fung C, Webeck LM, Sargent DB, Gologorsky MB, Chen Z, McDaniel MM, Kasal DN, McGinty JW, Barrow KA, Rich LM, Barilli A, Sabat M, Debley JS, Wu C, Myers R, Howitt MR, von Moltke J. Billipp TE, et al. Among authors: howitt mr. Immunity. 2024 May 6:S1074-7613(24)00144-4. doi: 10.1016/j.immuni.2024.03.023. Online ahead of print. Immunity. 2024. PMID: 38744291
Tropism for tuft cells determines immune promotion of norovirus pathogenesis.
Wilen CB, Lee S, Hsieh LL, Orchard RC, Desai C, Hykes BL Jr, McAllaster MR, Balce DR, Feehley T, Brestoff JR, Hickey CA, Yokoyama CC, Wang YT, MacDuff DA, Kreamalmayer D, Howitt MR, Neil JA, Cadwell K, Allen PM, Handley SA, van Lookeren Campagne M, Baldridge MT, Virgin HW. Wilen CB, et al. Among authors: howitt mr. Science. 2018 Apr 13;360(6385):204-208. doi: 10.1126/science.aar3799. Science. 2018. PMID: 29650672 Free PMC article.
Intestinal tuft cell immune privilege enables norovirus persistence.
Strine MS, Fagerberg E, Darcy PW, Barrón GM, Filler RB, Alfajaro MM, D'Angelo-Gavrish N, Wang F, Graziano VR, Menasché BL, Damo M, Wang YT, Howitt MR, Lee S, Joshi NS, Mucida D, Wilen CB. Strine MS, et al. Among authors: howitt mr. Sci Immunol. 2024 Mar 22;9(93):eadi7038. doi: 10.1126/sciimmunol.adi7038. Epub 2024 Mar 22. Sci Immunol. 2024. PMID: 38517952
19 results