Sternberg SH - Search Results

1

Targeted DNA integration in human cells without double-strand breaks using CRISPR-associated transposases.

Lampe GD, King RT, Halpin-Healy TS, Klompe SE, Hogan MI, Vo PLH, Tang S, Chavez A, Sternberg SH. Lampe GD, et al. Among authors: sternberg sh. Nat Biotechnol. 2024 Jan;42(1):87-98. doi: 10.1038/s41587-023-01748-1. Epub 2023 Mar 29. Nat Biotechnol. 2024. PMID: 36991112 Free PMC article.

2

DNA interrogation by the CRISPR RNA-guided endonuclease Cas9.

Sternberg SH, Redding S, Jinek M, Greene EC, Doudna JA. Sternberg SH, et al. Nature. 2014 Mar 6;507(7490):62-7. doi: 10.1038/nature13011. Epub 2014 Jan 29. Nature. 2014. PMID: 24476820 Free PMC article.

3

Programmable RNA recognition and cleavage by CRISPR/Cas9.

O'Connell MR, Oakes BL, Sternberg SH, East-Seletsky A, Kaplan M, Doudna JA. O'Connell MR, et al. Among authors: sternberg sh. Nature. 2014 Dec 11;516(7530):263-6. doi: 10.1038/nature13769. Epub 2014 Sep 28. Nature. 2014. PMID: 25274302 Free PMC article.

4

Conformational control of DNA target cleavage by CRISPR-Cas9.

Sternberg SH, LaFrance B, Kaplan M, Doudna JA. Sternberg SH, et al. Nature. 2015 Nov 5;527(7576):110-3. doi: 10.1038/nature15544. Epub 2015 Oct 28. Nature. 2015. PMID: 26524520 Free PMC article.

5

Harnessing "A Billion Years of Experimentation": The Ongoing Exploration and Exploitation of CRISPR-Cas Immune Systems.

Klompe SE, Sternberg SH. Klompe SE, et al. Among authors: sternberg sh. CRISPR J. 2018 Apr;1(2):141-158. doi: 10.1089/crispr.2018.0012. CRISPR J. 2018. PMID: 31021200 Free PMC article. Review.

6

Transposon-encoded CRISPR-Cas systems direct RNA-guided DNA integration.

Klompe SE, Vo PLH, Halpin-Healy TS, Sternberg SH. Klompe SE, et al. Among authors: sternberg sh. Nature. 2019 Jul;571(7764):219-225. doi: 10.1038/s41586-019-1323-z. Epub 2019 Jun 12. Nature. 2019. PMID: 31189177

7

Harnessing type I CRISPR-Cas systems for genome engineering in human cells.

Cameron P, Coons MM, Klompe SE, Lied AM, Smith SC, Vidal B, Donohoue PD, Rotstein T, Kohrs BW, Nyer DB, Kennedy R, Banh LM, Williams C, Toh MS, Irby MJ, Edwards LS, Lin CH, Owen ALG, Künne T, van der Oost J, Brouns SJJ, Slorach EM, Fuller CK, Gradia S, Kanner SB, May AP, Sternberg SH. Cameron P, et al. Among authors: sternberg sh. Nat Biotechnol. 2019 Dec;37(12):1471-1477. doi: 10.1038/s41587-019-0310-0. Epub 2019 Nov 18. Nat Biotechnol. 2019. PMID: 31740839

8

Structural basis of DNA targeting by a transposon-encoded CRISPR-Cas system.

Halpin-Healy TS, Klompe SE, Sternberg SH, Fernández IS. Halpin-Healy TS, et al. Among authors: sternberg sh. Nature. 2020 Jan;577(7789):271-274. doi: 10.1038/s41586-019-1849-0. Epub 2019 Dec 18. Nature. 2020. PMID: 31853065

9

Publisher Correction: Structural basis of DNA targeting by a transposon-encoded CRISPR-Cas system.

Halpin-Healy TS, Klompe SE, Sternberg SH, Fernández IS. Halpin-Healy TS, et al. Among authors: sternberg sh. Nature. 2020 Sep;585(7825):E12. doi: 10.1038/s41586-020-2662-5. Nature. 2020. PMID: 32843756

10

CRISPR RNA-guided integrases for high-efficiency, multiplexed bacterial genome engineering.

Vo PLH, Ronda C, Klompe SE, Chen EE, Acree C, Wang HH, Sternberg SH. Vo PLH, et al. Among authors: sternberg sh. Nat Biotechnol. 2021 Apr;39(4):480-489. doi: 10.1038/s41587-020-00745-y. Epub 2020 Nov 23. Nat Biotechnol. 2021. PMID: 33230293 Free PMC article.

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