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Combination therapy with vidaza and entinostat suppresses tumor growth and reprograms the epigenome in an orthotopic lung cancer model.
Belinsky SA, Grimes MJ, Picchi MA, Mitchell HD, Stidley CA, Tesfaigzi Y, Channell MM, Liu Y, Casero RA Jr, Baylin SB, Reed MD, Tellez CS, March TH. Belinsky SA, et al. Among authors: grimes mj. Cancer Res. 2011 Jan 15;71(2):454-62. doi: 10.1158/0008-5472.CAN-10-3184. Epub 2011 Jan 11. Cancer Res. 2011. PMID: 21224363 Free PMC article.
p53-Suppressed Oncogene TET1 Prevents Cellular Aging in Lung Cancer.
Filipczak PT, Leng S, Tellez CS, Do KC, Grimes MJ, Thomas CL, Walton-Filipczak SR, Picchi MA, Belinsky SA. Filipczak PT, et al. Among authors: grimes mj. Cancer Res. 2019 Apr 15;79(8):1758-1768. doi: 10.1158/0008-5472.CAN-18-1234. Epub 2019 Jan 8. Cancer Res. 2019. PMID: 30622117 Free PMC article.
5-Azacytidine inhaled dry powder formulation profoundly improves pharmacokinetics and efficacy for lung cancer therapy through genome reprogramming.
Kuehl PJ, Tellez CS, Grimes MJ, March TH, Tessema M, Revelli DA, Mallis LM, Dye WW, Sniegowski T, Badenoch A, Burke M, Dubose D, Vodak DT, Picchi MA, Belinsky SA. Kuehl PJ, et al. Among authors: grimes mj. Br J Cancer. 2020 Apr;122(8):1194-1204. doi: 10.1038/s41416-020-0765-2. Epub 2020 Feb 27. Br J Cancer. 2020. PMID: 32103148 Free PMC article.
23 results