Özvegy-Laczka C - Search Results

1

Organic Anion Transporting Polypeptide 3A1 (OATP3A1)-Gated Bio-Orthogonal Labeling of Intracellular Proteins.

Németh K, László Z, Biró A, Szatmári Á, Cserép GB, Várady G, Bakos É, Özvegy-Laczka C, Kele P. Németh K, et al. Among authors: ozvegy laczka c. Molecules. 2023 Mar 9;28(6):2521. doi: 10.3390/molecules28062521. Molecules. 2023. PMID: 36985493 Free PMC article.

2

High-affinity interaction of tyrosine kinase inhibitors with the ABCG2 multidrug transporter.

Ozvegy-Laczka C, Hegedus T, Várady G, Ujhelly O, Schuetz JD, Váradi A, Kéri G, Orfi L, Német K, Sarkadi B. Ozvegy-Laczka C, et al. Mol Pharmacol. 2004 Jun;65(6):1485-95. doi: 10.1124/mol.65.6.1485. Mol Pharmacol. 2004. PMID: 15155841

3

Function-dependent conformational changes of the ABCG2 multidrug transporter modify its interaction with a monoclonal antibody on the cell surface.

Ozvegy-Laczka C, Várady G, Köblös G, Ujhelly O, Cervenak J, Schuetz JD, Sorrentino BP, Koomen GJ, Váradi A, Német K, Sarkadi B. Ozvegy-Laczka C, et al. J Biol Chem. 2005 Feb 11;280(6):4219-27. doi: 10.1074/jbc.M411338200. Epub 2004 Nov 22. J Biol Chem. 2005. PMID: 15557326 Free article.

4

Multidrug transporter ABCG2 prevents tumor cell death induced by the epidermal growth factor receptor inhibitor Iressa (ZD1839, Gefitinib).

Elkind NB, Szentpétery Z, Apáti A, Ozvegy-Laczka C, Várady G, Ujhelly O, Szabó K, Homolya L, Váradi A, Buday L, Kéri G, Német K, Sarkadi B. Elkind NB, et al. Cancer Res. 2005 Mar 1;65(5):1770-7. doi: 10.1158/0008-5472.CAN-04-3303. Cancer Res. 2005. PMID: 15753373

5

Interaction with the 5D3 monoclonal antibody is regulated by intramolecular rearrangements but not by covalent dimer formation of the human ABCG2 multidrug transporter.

Ozvegy-Laczka C, Laczkó R, Hegedus C, Litman T, Várady G, Goda K, Hegedus T, Dokholyan NV, Sorrentino BP, Váradi A, Sarkadi B. Ozvegy-Laczka C, et al. J Biol Chem. 2008 Sep 19;283(38):26059-70. doi: 10.1074/jbc.M803230200. Epub 2008 Jul 21. J Biol Chem. 2008. PMID: 18644784 Free PMC article.

6

Antibody binding shift assay for rapid screening of drug interactions with the human ABCG2 multidrug transporter.

Telbisz Á, Hegedüs C, Özvegy-Laczka C, Goda K, Várady G, Takáts Z, Szabó E, Sorrentino BP, Váradi A, Sarkadi B. Telbisz Á, et al. Eur J Pharm Sci. 2012 Jan 23;45(1-2):101-9. doi: 10.1016/j.ejps.2011.10.021. Epub 2011 Nov 17. Eur J Pharm Sci. 2012. PMID: 22115866

7

Interaction of the EGFR inhibitors gefitinib, vandetanib, pelitinib and neratinib with the ABCG2 multidrug transporter: implications for the emergence and reversal of cancer drug resistance.

Hegedüs C, Truta-Feles K, Antalffy G, Várady G, Német K, Ozvegy-Laczka C, Kéri G, Orfi L, Szakács G, Settleman J, Váradi A, Sarkadi B. Hegedüs C, et al. Biochem Pharmacol. 2012 Aug 1;84(3):260-7. doi: 10.1016/j.bcp.2012.04.010. Epub 2012 Apr 21. Biochem Pharmacol. 2012. PMID: 22548830

8

Functional expression of the 11 human Organic Anion Transporting Polypeptides in insect cells reveals that sodium fluorescein is a general OATP substrate.

Patik I, Kovacsics D, Német O, Gera M, Várady G, Stieger B, Hagenbuch B, Szakács G, Özvegy-Laczka C. Patik I, et al. Biochem Pharmacol. 2015 Dec 15;98(4):649-58. doi: 10.1016/j.bcp.2015.09.015. Epub 2015 Sep 28. Biochem Pharmacol. 2015. PMID: 26415544 Free PMC article.

9

The role of organic anion transporting polypeptides in drug absorption, distribution, excretion and drug-drug interactions.

Kovacsics D, Patik I, Özvegy-Laczka C. Kovacsics D, et al. Expert Opin Drug Metab Toxicol. 2017 Apr;13(4):409-424. doi: 10.1080/17425255.2017.1253679. Epub 2016 Nov 9. Expert Opin Drug Metab Toxicol. 2017. PMID: 27783531 Review.

10

Influence of OATPs on Hepatic Disposition of Erlotinib Measured With Positron Emission Tomography.

Bauer M, Matsuda A, Wulkersdorfer B, Philippe C, Traxl A, Özvegy-Laczka C, Stanek J, Nics L, Klebermass EM, Poschner S, Jäger W, Patik I, Bakos É, Szakács G, Wadsak W, Hacker M, Zeitlinger M, Langer O. Bauer M, et al. Clin Pharmacol Ther. 2018 Jul;104(1):139-147. doi: 10.1002/cpt.888. Epub 2017 Nov 3. Clin Pharmacol Ther. 2018. PMID: 28940241 Free PMC article.

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