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Tissue-specific enhancer-gene maps from multimodal single-cell data identify causal disease alleles.
Sakaue S, Weinand K, Isaac S, Dey KK, Jagadeesh K, Kanai M, Watts GFM, Zhu Z; Accelerating Medicines Partnership® RA/SLE Program and Network; Brenner MB, McDavid A, Donlin LT, Wei K, Price AL, Raychaudhuri S. Sakaue S, et al. Among authors: price al. Nat Genet. 2024 Apr;56(4):615-626. doi: 10.1038/s41588-024-01682-1. Epub 2024 Apr 9. Nat Genet. 2024. PMID: 38594305
Implementation of a Multidimensional Strategy to Reduce Post-PCI Bleeding Risk.
Price AL, Amin AP, Rogers S, Messenger JC, Moussa ID, Miller JM, Jennings J, Masoudi FA, Abbott JD, Young R, Wojdyla DM, Rao SV. Price AL, et al. Circ Cardiovasc Interv. 2024 Mar;17(3):e013003. doi: 10.1161/CIRCINTERVENTIONS.123.013003. Epub 2024 Feb 27. Circ Cardiovasc Interv. 2024. PMID: 38410946 Free PMC article. Review.
Distinguishing different psychiatric disorders using DDx-PRS.
Peyrot WJ, Panagiotaropoulou G, Olde Loohuis LM, Adams MJ, Awasthi S, Ge T, McIntosh AM, Mitchell BL, Mullins N, O'Connell KS, Penninx BWJH, Posthuma D, Ripke S, Ruderfer DM, Uffelmann E, Vilhjalmsson BJ, Zhu Z; Schizophrenia Working Group of the Psychiatric Genomics Consortium; Bipolar Disorder Working Group of the Psychiatric Genomics Consortium; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium; Smoller JW, Price AL. Peyrot WJ, et al. Among authors: price al. medRxiv [Preprint]. 2024 Feb 4:2024.02.02.24302228. doi: 10.1101/2024.02.02.24302228. medRxiv. 2024. PMID: 38352307 Free PMC article. Preprint.
Estimating Disorder Probability Based on Polygenic Prediction Using the BPC Approach.
Uffelmann E; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium; Schizophrenia Working Group of the Psychiatric Genomics Consortium; Price AL, Posthuma D, Peyrot WJ. Uffelmann E, et al. Among authors: price al. medRxiv [Preprint]. 2024 Jan 13:2024.01.12.24301157. doi: 10.1101/2024.01.12.24301157. medRxiv. 2024. PMID: 38260678 Free PMC article. Preprint.
Pervasive correlations between causal disease effects of proximal SNPs vary with functional annotations and implicate stabilizing selection.
Zhang MJ, Durvasula A, Chiang C, Koch EM, Strober BJ, Shi H, Barton AR, Kim SS, Weissbrod O, Loh PR, Gazal S, Sunyaev S, Price AL. Zhang MJ, et al. Among authors: price al. medRxiv [Preprint]. 2023 Dec 4:2023.12.04.23299391. doi: 10.1101/2023.12.04.23299391. medRxiv. 2023. PMID: 38106023 Free PMC article. Preprint.
203 results