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The evolutionary conserved miR-137/325 tandem mediates obesity-induced hypogonadism and metabolic comorbidities by repressing hypothalamic kisspeptin.
Avendaño MS, Perdices-Lopez C, Guerrero-Ruiz Y, Ruiz-Pino F, Rodriguez-Sanchez AB, Sanchez-Tapia MJ, Sobrino V, Pineda R, Barroso A, Correa-Sáez A, Lara-Chica M, Fernandez-Garcia JC, García-Redondo AB, Hernanz R, Ruiz-Cruz M, Garcia-Galiano D, Pitteloud N, Calzado MA, Briones AM, Vázquez MJ, Tena-Sempere M. Avendaño MS, et al. Among authors: sobrino v. Metabolism. 2024 May 8:155932. doi: 10.1016/j.metabol.2024.155932. Online ahead of print. Metabolism. 2024. PMID: 38729600 Free article.
Dicer ablation in Kiss1 neurons impairs puberty and fertility preferentially in female mice.
Roa J, Ruiz-Cruz M, Ruiz-Pino F, Onieva R, Vazquez MJ, Sanchez-Tapia MJ, Ruiz-Rodriguez JM, Sobrino V, Barroso A, Heras V, Velasco I, Perdices-Lopez C, Ohlsson C, Avendaño MS, Prevot V, Poutanen M, Pinilla L, Gaytan F, Tena-Sempere M. Roa J, et al. Among authors: sobrino v. Nat Commun. 2022 Aug 9;13(1):4663. doi: 10.1038/s41467-022-32347-4. Nat Commun. 2022. PMID: 35945211 Free PMC article.
Connecting nutritional deprivation and pubertal inhibition via GRK2-mediated repression of kisspeptin actions in GnRH neurons.
Perdices-Lopez C, Avendaño MS, Barroso A, Gaytán F, Ruiz-Pino F, Vázquez MJ, Leon S, Song YB, Sobrino V, Heras V, Romero-Ruiz A, Roa J, Mayor F Jr, Murga C, Pinilla L, Kaiser UB, Tena-Sempere M. Perdices-Lopez C, et al. Among authors: sobrino v. Metabolism. 2022 Apr;129:155141. doi: 10.1016/j.metabol.2022.155141. Epub 2022 Jan 22. Metabolism. 2022. PMID: 35074314 Free PMC article.
Neurotransmitter Modulation of Carotid Body Germinal Niche.
Sobrino V, Platero-Luengo A, Annese V, Navarro-Guerrero E, González-Rodríguez P, López-Barneo J, Pardal R. Sobrino V, et al. Int J Mol Sci. 2020 Nov 3;21(21):8231. doi: 10.3390/ijms21218231. Int J Mol Sci. 2020. PMID: 33153142 Free PMC article. Review.
14 results