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Development of K562 cell clones expressing beta-globin mRNA carrying the beta039 thalassaemia mutation for the screening of correctors of stop-codon mutations.
Salvatori F, Cantale V, Breveglieri G, Zuccato C, Finotti A, Bianchi N, Borgatti M, Feriotto G, Destro F, Canella A, Breda L, Rivella S, Gambari R. Salvatori F, et al. Among authors: breveglieri g. Biotechnol Appl Biochem. 2009 Jul 9;54(1):41-52. doi: 10.1042/BA20080266. Biotechnol Appl Biochem. 2009. PMID: 19216718 Free PMC article.
Development and characterization of K562 cell clones expressing BCL11A-XL: Decreased hemoglobin production with fetal hemoglobin inducers and its rescue with mithramycin.
Finotti A, Gasparello J, Breveglieri G, Cosenza LC, Montagner G, Bresciani A, Altamura S, Bianchi N, Martini E, Gallerani E, Borgatti M, Gambari R. Finotti A, et al. Among authors: breveglieri g. Exp Hematol. 2015 Dec;43(12):1062-1071.e3. doi: 10.1016/j.exphem.2015.08.011. Epub 2015 Sep 3. Exp Hematol. 2015. PMID: 26342260 Free PMC article.
Development and characterization of cellular biosensors for HTS of erythroid differentiation inducers targeting the transcriptional activity of γ-globin and β-globin gene promoters.
Breveglieri G, Salvatori F, Finotti A, Cosenza LC, Zuccato C, Bianchi N, Breda L, Rivella S, Bresciani A, Bisbocci M, Borgatti M, Gambari R. Breveglieri G, et al. Anal Bioanal Chem. 2019 Nov;411(29):7669-7680. doi: 10.1007/s00216-019-01959-z. Epub 2019 Jul 4. Anal Bioanal Chem. 2019. PMID: 31273412
The rs368698783 (G>A) Polymorphism Affecting LYAR Binding to the Aγ-Globin Gene Is Associated with High Fetal Hemoglobin (HbF) in β-Thalassemia Erythroid Precursor Cells Treated with HbF Inducers.
Zuccato C, Cosenza LC, Zurlo M, Breveglieri G, Bianchi N, Lampronti I, Gasparello J, Scapoli C, Borgatti M, Finotti A, Gambari R. Zuccato C, et al. Among authors: breveglieri g. Int J Mol Sci. 2023 Jan 1;24(1):776. doi: 10.3390/ijms24010776. Int J Mol Sci. 2023. PMID: 36614221 Free PMC article.
A novel frameshift mutation (+A) at codon 18 of the beta-globin gene associated with high persistence of fetal hemoglobin phenotype and deltabeta-thalassemia.
Feriotto G, Salvatori F, Finotti A, Breveglieri G, Venturi M, Zuccato C, Bianchi N, Borgatti M, Lampronti I, Mancini I, Massei F, Favre C, Gambari R. Feriotto G, et al. Among authors: breveglieri g. Acta Haematol. 2008;119(1):28-37. doi: 10.1159/000114204. Epub 2008 Jan 30. Acta Haematol. 2008. PMID: 18230963
Bergamot (Citrus bergamia Risso) fruit extracts as γ-globin gene expression inducers: phytochemical and functional perspectives.
Guerrini A, Lampronti I, Bianchi N, Zuccato C, Breveglieri G, Salvatori F, Mancini I, Rossi D, Potenza R, Chiavilli F, Sacchetti G, Gambari R, Borgatti M. Guerrini A, et al. Among authors: breveglieri g. J Agric Food Chem. 2009 May 27;57(10):4103-11. doi: 10.1021/jf803489p. Epub 2009 Apr 16. J Agric Food Chem. 2009. PMID: 19371028
Increase in gamma-globin mRNA content in human erythroid cells treated with angelicin analogs.
Lampronti I, Bianchi N, Zuccato C, Dall'Acqua F, Vedaldi D, Viola G, Potenza R, Chiavilli F, Breveglieri G, Borgatti M, Finotti A, Feriotto G, Salvatori F, Gambari R. Lampronti I, et al. Among authors: breveglieri g. Int J Hematol. 2009 Oct;90(3):318-327. doi: 10.1007/s12185-009-0422-2. Epub 2009 Sep 25. Int J Hematol. 2009. PMID: 19777196
Production of beta-globin and adult hemoglobin following G418 treatment of erythroid precursor cells from homozygous beta(0)39 thalassemia patients.
Salvatori F, Breveglieri G, Zuccato C, Finotti A, Bianchi N, Borgatti M, Feriotto G, Destro F, Canella A, Brognara E, Lampronti I, Breda L, Rivella S, Gambari R. Salvatori F, et al. Among authors: breveglieri g. Am J Hematol. 2009 Nov;84(11):720-8. doi: 10.1002/ajh.21539. Am J Hematol. 2009. PMID: 19810011 Free PMC article.
A combined approach for β-thalassemia based on gene therapy-mediated adult hemoglobin (HbA) production and fetal hemoglobin (HbF) induction.
Zuccato C, Breda L, Salvatori F, Breveglieri G, Gardenghi S, Bianchi N, Brognara E, Lampronti I, Borgatti M, Rivella S, Gambari R. Zuccato C, et al. Among authors: breveglieri g. Ann Hematol. 2012 Aug;91(8):1201-13. doi: 10.1007/s00277-012-1430-5. Epub 2012 Mar 31. Ann Hematol. 2012. PMID: 22460946 Free PMC article.
51 results