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Upregulation of HSP27 in a transgenic model of ALS.
Vleminckx V, Van Damme P, Goffin K, Delye H, Van Den Bosch L, Robberecht W. Vleminckx V, et al. Among authors: van damme p, van den bosch l. J Neuropathol Exp Neurol. 2002 Nov;61(11):968-74. doi: 10.1093/jnen/61.11.968. J Neuropathol Exp Neurol. 2002. PMID: 12430713
The neurobiology of amyotrophic lateral sclerosis.
Bento-Abreu A, Van Damme P, Van Den Bosch L, Robberecht W. Bento-Abreu A, et al. Among authors: van damme p, van den bosch l. Eur J Neurosci. 2010 Jun;31(12):2247-65. doi: 10.1111/j.1460-9568.2010.07260.x. Epub 2010 Jun 7. Eur J Neurosci. 2010. PMID: 20529130 Review.
Amyloid precursor protein mutation E682K at the alternative β-secretase cleavage β'-site increases Aβ generation.
Zhou L, Brouwers N, Benilova I, Vandersteen A, Mercken M, Van Laere K, Van Damme P, Demedts D, Van Leuven F, Sleegers K, Broersen K, Van Broeckhoven C, Vandenberghe R, De Strooper B. Zhou L, et al. Among authors: van laere k, van leuven f, van damme p, van broeckhoven c. EMBO Mol Med. 2011 May;3(5):291-302. doi: 10.1002/emmm.201100138. Epub 2011 Apr 15. EMBO Mol Med. 2011. PMID: 21500352 Free PMC article.
Whole-genome sequencing reveals a coding non-pathogenic variant tagging a non-coding pathogenic hexanucleotide repeat expansion in C9orf72 as cause of amyotrophic lateral sclerosis.
Herdewyn S, Zhao H, Moisse M, Race V, Matthijs G, Reumers J, Kusters B, Schelhaas HJ, van den Berg LH, Goris A, Robberecht W, Lambrechts D, Van Damme P. Herdewyn S, et al. Among authors: van den berg lh, van damme p. Hum Mol Genet. 2012 Jun 1;21(11):2412-9. doi: 10.1093/hmg/dds055. Epub 2012 Feb 17. Hum Mol Genet. 2012. PMID: 22343411 Free PMC article.
EPHA4 is a disease modifier of amyotrophic lateral sclerosis in animal models and in humans.
Van Hoecke A, Schoonaert L, Lemmens R, Timmers M, Staats KA, Laird AS, Peeters E, Philips T, Goris A, Dubois B, Andersen PM, Al-Chalabi A, Thijs V, Turnley AM, van Vught PW, Veldink JH, Hardiman O, Van Den Bosch L, Gonzalez-Perez P, Van Damme P, Brown RH Jr, van den Berg LH, Robberecht W. Van Hoecke A, et al. Among authors: van damme p, van den berg lh, van vught pw, van den bosch l. Nat Med. 2012 Sep;18(9):1418-22. doi: 10.1038/nm.2901. Nat Med. 2012. PMID: 22922411
Neuronal overexpression of IP₃ receptor 2 is detrimental in mutant SOD1 mice.
Staats KA, Bogaert E, Hersmus N, Jaspers T, Luyten T, Bultynck G, Parys JB, Hisatsune C, Mikoshiba K, Van Damme P, Robberecht W, Van Den Bosch L. Staats KA, et al. Among authors: van damme p, van den bosch l. Biochem Biophys Res Commun. 2012 Dec 14;429(3-4):210-3. doi: 10.1016/j.bbrc.2012.10.094. Epub 2012 Nov 3. Biochem Biophys Res Commun. 2012. PMID: 23131553
Hdac6 deletion delays disease progression in the SOD1G93A mouse model of ALS.
Taes I, Timmers M, Hersmus N, Bento-Abreu A, Van Den Bosch L, Van Damme P, Auwerx J, Robberecht W. Taes I, et al. Among authors: van damme p, van den bosch l. Hum Mol Genet. 2013 May 1;22(9):1783-90. doi: 10.1093/hmg/ddt028. Epub 2013 Jan 30. Hum Mol Genet. 2013. PMID: 23364049 Free article.
1,228 results