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The combination of colistin and doripenem is synergistic against Klebsiella pneumoniae at multiple inocula and suppresses colistin resistance in an in vitro pharmacokinetic/pharmacodynamic model.
Deris ZZ, Yu HH, Davis K, Soon RL, Jacob J, Ku CK, Poudyal A, Bergen PJ, Tsuji BT, Bulitta JB, Forrest A, Paterson DL, Velkov T, Li J, Nation RL. Deris ZZ, et al. Among authors: yu hh. Antimicrob Agents Chemother. 2012 Oct;56(10):5103-12. doi: 10.1128/AAC.01064-12. Epub 2012 Jul 16. Antimicrob Agents Chemother. 2012. PMID: 22802247 Free PMC article.
Discovery of mcr-1-Mediated Colistin Resistance in a Highly Virulent Escherichia coli Lineage.
Forde BM, Zowawi HM, Harris PNA, Roberts L, Ibrahim E, Shaikh N, Deshmukh A, Sid Ahmed MA, Al Maslamani M, Cottrell K, Trembizki E, Sundac L, Yu HH, Li J, Schembri MA, Whiley DM, Paterson DL, Beatson SA. Forde BM, et al. Among authors: yu hh. mSphere. 2018 Oct 10;3(5):e00486-18. doi: 10.1128/mSphere.00486-18. mSphere. 2018. PMID: 30305321 Free PMC article.
Novel Polymyxin Combination with the Antiretroviral Zidovudine Exerts Synergistic Killing against NDM-Producing Multidrug-Resistant Klebsiella pneumoniae.
Lin YW, Abdul Rahim N, Zhao J, Han ML, Yu HH, Wickremasinghe H, Chen K, Wang J, Paterson DL, Zhu Y, Rao GG, Zhou QT, Forrest A, Velkov T, Li J. Lin YW, et al. Among authors: yu hh. Antimicrob Agents Chemother. 2019 Mar 27;63(4):e02176-18. doi: 10.1128/AAC.02176-18. Print 2019 Apr. Antimicrob Agents Chemother. 2019. PMID: 30670431 Free PMC article.
657 results