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Neutron-encoded diubiquitins to profile linkage selectivity of deubiquitinating enzymes.
van Tol BDM, van Doodewaerd BR, Lageveen-Kammeijer GSM, Jansen BC, Talavera Ormeño CMP, Hekking PJM, Sapmaz A, Kim RQ, Moutsiopoulou A, Komander D, Wuhrer M, van der Heden van Noort GJ, Ovaa H, Geurink PP. van Tol BDM, et al. Among authors: kim rq. Nat Commun. 2023 Mar 25;14(1):1661. doi: 10.1038/s41467-023-37363-6. Nat Commun. 2023. PMID: 36966155 Free PMC article.
Chemical Toolkit for PARK7: Potent, Selective, and High-Throughput.
Jia Y, Kim RQ, Kooij R, Ovaa H, Sapmaz A, Geurink PP. Jia Y, et al. Among authors: kim rq. J Med Chem. 2022 Oct 13;65(19):13288-13304. doi: 10.1021/acs.jmedchem.2c01113. Epub 2022 Sep 23. J Med Chem. 2022. PMID: 36149939 Free PMC article.
Arginine ADP-Ribosylation: Chemical Synthesis of Post-Translationally Modified Ubiquitin Proteins.
Voorneveld J, Kloet MS, Wijngaarden S, Kim RQ, Moutsiopoulou A, Verdegaal M, Misra M, Đikić I, van der Marel GA, Overkleeft HS, Filippov DV, van der Heden van Noort GJ. Voorneveld J, et al. Among authors: kim rq. J Am Chem Soc. 2022 Nov 16;144(45):20582-20589. doi: 10.1021/jacs.2c06249. Epub 2022 Nov 1. J Am Chem Soc. 2022. PMID: 36318515 Free PMC article.
RNF26 binds perinuclear vimentin filaments to integrate ER and endolysosomal responses to proteotoxic stress.
Cremer T, Voortman LM, Bos E, Jongsma ML, Ter Haar LR, Akkermans JJ, Talavera Ormeño CM, Wijdeven RH, de Vries J, Kim RQ, Janssen GM, van Veelen PA, Koning RI, Neefjes J, Berlin I. Cremer T, et al. Among authors: kim rq. EMBO J. 2023 Sep 18;42(18):e111252. doi: 10.15252/embj.2022111252. Epub 2023 Jul 31. EMBO J. 2023. PMID: 37519262 Free PMC article.
Cellular Validation of a Chemically Improved Inhibitor Identifies Monoubiquitination on OTUB2.
Gan J, de Vries J, Akkermans JJLL, Mohammed Y, Tjokrodirijo RTN, de Ru AH, Kim RQ, Vargas DA, Pol V, Fasan R, van Veelen PA, Neefjes J, van Dam H, Ovaa H, Sapmaz A, Geurink PP. Gan J, et al. Among authors: kim rq. ACS Chem Biol. 2023 Sep 15;18(9):2003-2013. doi: 10.1021/acschembio.3c00227. Epub 2023 Aug 29. ACS Chem Biol. 2023. PMID: 37642399 Free PMC article.
20 results