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Novel gold(I) complexes induce apoptosis in leukemia cells via the ROS-induced mitochondrial pathway with an upregulation of Harakiri and overcome multi drug resistances in leukemia and lymphoma cells and sensitize drug resistant tumor cells to apoptosis in vitro.
Ahrweiler-Sawaryn MC, Biswas A, Frias C, Frias J, Wilke NL, Wilke N, Berkessel A, Prokop A. Ahrweiler-Sawaryn MC, et al. Biomed Pharmacother. 2023 May;161:114507. doi: 10.1016/j.biopha.2023.114507. Epub 2023 Mar 21. Biomed Pharmacother. 2023. PMID: 36958194 Free article.