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Page 1
Translocation t(6;7) in AML-M4 cell line GDM-1 results in MNX1 activation through enhancer-hijacking.
Weichenhan D, Riedel A, Meinen C, Basic A, Toth R, Bähr M, Lutsik P, Hey J, Sollier E, Toprak UH, Kelekçi S, Lin YY, Hakobyan M, Touzart A, Goyal A, Wierzbinska JA, Schlesner M, Westermann F, Lipka DB, Plass C. Weichenhan D, et al. Among authors: wierzbinska ja. Leukemia. 2023 May;37(5):1147-1150. doi: 10.1038/s41375-023-01865-5. Epub 2023 Mar 22. Leukemia. 2023. PMID: 36949154 Free PMC article. No abstract available.
Methylome-based cell-of-origin modeling (Methyl-COOM) identifies aberrant expression of immune regulatory molecules in CLL.
Wierzbinska JA, Toth R, Ishaque N, Rippe K, Mallm JP, Klett LC, Mertens D, Zenz T, Hielscher T, Seifert M, Küppers R, Assenov Y, Lutsik P, Stilgenbauer S, Roessner PM, Seiffert M, Byrd J, Oakes CC, Plass C, Lipka DB. Wierzbinska JA, et al. Genome Med. 2020 Mar 18;12(1):29. doi: 10.1186/s13073-020-00724-7. Genome Med. 2020. PMID: 32188505 Free PMC article.
RAS-pathway mutation patterns define epigenetic subclasses in juvenile myelomonocytic leukemia.
Lipka DB, Witte T, Toth R, Yang J, Wiesenfarth M, Nöllke P, Fischer A, Brocks D, Gu Z, Park J, Strahm B, Wlodarski M, Yoshimi A, Claus R, Lübbert M, Busch H, Boerries M, Hartmann M, Schönung M, Kilik U, Langstein J, Wierzbinska JA, Pabst C, Garg S, Catalá A, De Moerloose B, Dworzak M, Hasle H, Locatelli F, Masetti R, Schmugge M, Smith O, Stary J, Ussowicz M, van den Heuvel-Eibrink MM, Assenov Y, Schlesner M, Niemeyer C, Flotho C, Plass C. Lipka DB, et al. Among authors: wierzbinska ja. Nat Commun. 2017 Dec 19;8(1):2126. doi: 10.1038/s41467-017-02177-w. Nat Commun. 2017. PMID: 29259247 Free PMC article. Clinical Trial.
Epigenetic silencing of AKAP12 in juvenile myelomonocytic leukemia.
Wilhelm T, Lipka DB, Witte T, Wierzbinska JA, Fluhr S, Helf M, Mücke O, Claus R, Konermann C, Nöllke P, Niemeyer CM, Flotho C, Plass C. Wilhelm T, et al. Among authors: wierzbinska ja. Epigenetics. 2016;11(2):110-9. doi: 10.1080/15592294.2016.1145327. Epub 2016 Feb 18. Epigenetics. 2016. PMID: 26891149 Free PMC article.