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Page 1
Translocation t(6;7) in AML-M4 cell line GDM-1 results in MNX1 activation through enhancer-hijacking.
Weichenhan D, Riedel A, Meinen C, Basic A, Toth R, Bähr M, Lutsik P, Hey J, Sollier E, Toprak UH, Kelekçi S, Lin YY, Hakobyan M, Touzart A, Goyal A, Wierzbinska JA, Schlesner M, Westermann F, Lipka DB, Plass C. Weichenhan D, et al. Among authors: touzart a. Leukemia. 2023 May;37(5):1147-1150. doi: 10.1038/s41375-023-01865-5. Epub 2023 Mar 22. Leukemia. 2023. PMID: 36949154 Free PMC article. No abstract available.
Toward Pediatric T Lymphoblastic Lymphoma Stratification Based on Minimal Disseminated Disease and NOTCH1/FBXW7 Status.
Trinquand A, Plesa A, Abdo C, Subtil F, Aladjidi N, Rigaud C, Touzart A, Lhermitte L, Petit A, Michaux K, Jung C, Chassagne-Clement C, Asnafi V, Bertrand Y, Garnier N, Macintyre E. Trinquand A, et al. Among authors: touzart a. Hemasphere. 2021 Sep 6;5(10):e641. doi: 10.1097/HS9.0000000000000641. eCollection 2021 Oct. Hemasphere. 2021. PMID: 34514345 Free PMC article.
Minimal residual disease monitoring by 8-color flow cytometry in mantle cell lymphoma: an EU-MCL and LYSA study.
Cheminant M, Derrieux C, Touzart A, Schmit S, Grenier A, Trinquand A, Delfau-Larue MH, Lhermitte L, Thieblemont C, Ribrag V, Cheze S, Sanhes L, Jardin F, Lefrère F, Delarue R, Hoster E, Dreyling M, Asnafi V, Hermine O, Macintyre E. Cheminant M, et al. Among authors: touzart a. Haematologica. 2016 Mar;101(3):336-45. doi: 10.3324/haematol.2015.134957. Epub 2015 Dec 24. Haematologica. 2016. PMID: 26703963 Free PMC article. Clinical Trial.
Epigenetic analysis of patients with T-ALL identifies poor outcomes and a hypomethylating agent-responsive subgroup.
Touzart A, Mayakonda A, Smith C, Hey J, Toth R, Cieslak A, Andrieu GP, Tran Quang C, Latiri M, Ghysdael J, Spicuglia S, Dombret H, Ifrah N, Macintyre E, Lutsik P, Boissel N, Plass C, Asnafi V. Touzart A, et al. Sci Transl Med. 2021 May 26;13(595):eabc4834. doi: 10.1126/scitranslmed.abc4834. Sci Transl Med. 2021. PMID: 34039737 Free article. Clinical Trial.
TAL1 activation in T-cell acute lymphoblastic leukemia: a novel oncogenic 3' neo-enhancer.
Smith C, Goyal A, Weichenhan D, Allemand E, Mayakonda A, Toprak U, Riedel A, Balducci E, Manojkumar M, Pejkovska A, Mücke O, Sollier E, Bakr A, Breuer K, Lutsik P, Hermine O, Spicuglia S, Asnafi V, Plass C, Touzart A. Smith C, et al. Among authors: touzart a. Haematologica. 2023 May 1;108(5):1259-1271. doi: 10.3324/haematol.2022.281583. Haematologica. 2023. PMID: 36632736 Free PMC article.
Harnessing the MYB-dependent TAL1 5'super-enhancer for targeted therapy in T-ALL.
Smith C, Touzart A, Simonin M, Tran-Quang C, Hypolite G, Latiri M, Andrieu GP, Balducci E, Dourthe MÉ, Goyal A, Huguet F, Petit A, Ifrah N, Baruchel A, Dombret H, Macintyre E, Plass C, Ghysdael J, Boissel N, Asnafi V. Smith C, et al. Among authors: touzart a. Mol Cancer. 2023 Jan 18;22(1):12. doi: 10.1186/s12943-022-01701-x. Mol Cancer. 2023. PMID: 36650499 Free PMC article.
Adult T-cell acute lymphoblastic leukemias with IL7R pathway mutations are slow-responders who do not benefit from allogeneic stem-cell transplantation.
Kim R, Boissel N, Touzart A, Leguay T, Thonier F, Thomas X, Raffoux E, Huguet F, Villarese P, Fourrage C, Passini L, Hunault M, Lepretre S, Chevallier P, Braun T, Lhéritier V, Chantepie S, Maury S, Escoffre M, Tavernier E, Chalandon Y, Graux C, Macintyre E, Ifrah N, Asnafi V, Dombret H, Lhermitte L; on behalf the GRAALL group. Kim R, et al. Among authors: touzart a. Leukemia. 2020 Jul;34(7):1730-1740. doi: 10.1038/s41375-019-0685-4. Epub 2020 Jan 28. Leukemia. 2020. PMID: 31992840 Clinical Trial.
TREC mediated oncogenesis in human immature T lymphoid malignancies preferentially involves ZFP36L2.
Balducci E, Steimlé T, Smith C, Villarese P, Feroul M, Payet-Bornet D, Kaltenbach S, Couronné L, Lhermitte L, Touzart A, Dourthe ME, Simonin M, Baruchel A, Dombret H, Ifrah N, Boissel N, Nadel B, Macintyre E, Cieslak A, Asnafi V. Balducci E, et al. Among authors: touzart a. Mol Cancer. 2023 Jul 10;22(1):108. doi: 10.1186/s12943-023-01794-y. Mol Cancer. 2023. PMID: 37430263 Free PMC article.
Blueprint of human thymopoiesis reveals molecular mechanisms of stage-specific TCR enhancer activation.
Cieslak A, Charbonnier G, Tesio M, Mathieu EL, Belhocine M, Touzart A, Smith C, Hypolite G, Andrieu GP, Martens JHA, Janssen-Megens E, Gut M, Gut I, Boissel N, Petit A, Puthier D, Macintyre E, Stunnenberg HG, Spicuglia S, Asnafi V. Cieslak A, et al. Among authors: touzart a. J Exp Med. 2020 Sep 7;217(9):e20192360. doi: 10.1084/jem.20192360. J Exp Med. 2020. PMID: 32667968 Free PMC article.
NAP1L1-MLLT10 is a rare recurrent translocation that is associated with HOXA activation and poor treatment response in T-cell acute lymphoblastic leukaemia.
Bond J, Touzart A, Cieslak A, Trinquand A, Marchand T, Escoffre M, Contet A, Muller M, Schmitt C, Fest T, Asnafi V, Macintyre E. Bond J, et al. Among authors: touzart a. Br J Haematol. 2016 Aug;174(3):470-3. doi: 10.1111/bjh.13772. Epub 2015 Oct 12. Br J Haematol. 2016. PMID: 26455581 Free article. No abstract available.
34 results