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Human PIK3R1 mutations disrupt lymphocyte differentiation to cause activated PI3Kδ syndrome 2.
Nguyen T, Lau A, Bier J, Cooke KC, Lenthall H, Ruiz-Diaz S, Avery DT, Brigden H, Zahra D, Sewell WA, Droney L, Okada S, Asano T, Abolhassani H, Chavoshzadeh Z, Abraham RS, Rajapakse N, Klee EW, Church JA, Williams A, Wong M, Burkhart C, Uzel G, Croucher DR, James DE, Ma CS, Brink R, Tangye SG, Deenick EK. Nguyen T, et al. Among authors: cooke kc. J Exp Med. 2023 Jun 5;220(6):e20221020. doi: 10.1084/jem.20221020. Epub 2023 Mar 21. J Exp Med. 2023. PMID: 36943234 Free PMC article.
Membrane Topology of Trafficking Regulator of GLUT4 1 (TRARG1).
Duan X, Krycer JR, Cooke KC, Yang G, James DE, Fazakerley DJ. Duan X, et al. Among authors: cooke kc. Biochemistry. 2018 Jul 3;57(26):3606-3615. doi: 10.1021/acs.biochem.8b00361. Epub 2018 Jun 7. Biochemistry. 2018. PMID: 29787242
RagC phosphorylation autoregulates mTOR complex 1.
Yang G, Humphrey SJ, Murashige DS, Francis D, Wang QP, Cooke KC, Neely GG, James DE. Yang G, et al. Among authors: cooke kc. EMBO J. 2019 Feb 1;38(3):e99548. doi: 10.15252/embj.201899548. Epub 2018 Dec 14. EMBO J. 2019. PMID: 30552228 Free PMC article.
ABHD15 regulates adipose tissue lipolysis and hepatic lipid accumulation.
Stöckli J, Zadoorian A, Cooke KC, Deshpande V, Yau B, Herrmann G, Kebede MA, Humphrey SJ, James DE. Stöckli J, et al. Among authors: cooke kc. Mol Metab. 2019 Jul;25:83-94. doi: 10.1016/j.molmet.2019.05.002. Epub 2019 May 6. Mol Metab. 2019. PMID: 31105056 Free PMC article.
Phosphoproteomics reveals conserved exercise-stimulated signaling and AMPK regulation of store-operated calcium entry.
Nelson ME, Parker BL, Burchfield JG, Hoffman NJ, Needham EJ, Cooke KC, Naim T, Sylow L, Ling NX, Francis D, Norris DM, Chaudhuri R, Oakhill JS, Richter EA, Lynch GS, Stöckli J, James DE. Nelson ME, et al. Among authors: cooke kc. EMBO J. 2019 Dec 16;38(24):e102578. doi: 10.15252/embj.2019102578. Epub 2019 Aug 5. EMBO J. 2019. PMID: 31381180 Free PMC article.
25 results