Hypoxic postconditioning activates the Wnt/β-catenin pathway and protects against transient global cerebral ischemia through Dkk1 Inhibition and GSK-3β inactivation.
Zhan L, Liu D, Wen H, Hu J, Pang T, Sun W, Xu E.
Zhan L, et al. Among authors: wen h.
FASEB J. 2019 Aug;33(8):9291-9307. doi: 10.1096/fj.201802633R. Epub 2019 May 23.
FASEB J. 2019.
PMID: 31120770
These results suggest that activation of the Wnt/beta-catenin pathway through Dkk1 inhibition and PI3K/protein kinase B pathway-mediated GSK-3beta inactivation contributes to the neuroprotection of HPC against tGCI.-Zhan, L., Liu, D., Wen, H., Hu, J., Pang, T., Sun, …
These results suggest that activation of the Wnt/beta-catenin pathway through Dkk1 inhibition and PI3K/protein kinase B pathway-mediated GSK …