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Loss of H3K9 trimethylation alters chromosome compaction and transcription factor retention during mitosis.
Djeghloul D, Dimond A, Cheriyamkunnel S, Kramer H, Patel B, Brown K, Montoya A, Whilding C, Wang YF, Futschik ME, Veland N, Montavon T, Jenuwein T, Merkenschlager M, Fisher AG. Djeghloul D, et al. Among authors: kramer h. Nat Struct Mol Biol. 2023 Apr;30(4):489-501. doi: 10.1038/s41594-023-00943-7. Epub 2023 Mar 20. Nat Struct Mol Biol. 2023. PMID: 36941433 Free PMC article.
Identifying proteins bound to native mitotic ESC chromosomes reveals chromatin repressors are important for compaction.
Djeghloul D, Patel B, Kramer H, Dimond A, Whilding C, Brown K, Kohler AC, Feytout A, Veland N, Elliott J, Bharat TAM, Tarafder AK, Löwe J, Ng BL, Guo Y, Guy J, Huseyin MK, Klose RJ, Merkenschlager M, Fisher AG. Djeghloul D, et al. Among authors: kramer h. Nat Commun. 2020 Aug 17;11(1):4118. doi: 10.1038/s41467-020-17823-z. Nat Commun. 2020. PMID: 32807789 Free PMC article.
A conserved ATP- and Scc2/4-dependent activity for cohesin in tethering DNA molecules.
Gutierrez-Escribano P, Newton MD, Llauró A, Huber J, Tanasie L, Davy J, Aly I, Aramayo R, Montoya A, Kramer H, Stigler J, Rueda DS, Aragon L. Gutierrez-Escribano P, et al. Among authors: kramer h. Sci Adv. 2019 Nov 27;5(11):eaay6804. doi: 10.1126/sciadv.aay6804. eCollection 2019 Nov. Sci Adv. 2019. PMID: 31807710 Free PMC article.
Snapshots of actin and tubulin folding inside the TRiC chaperonin.
Kelly JJ, Tranter D, Pardon E, Chi G, Kramer H, Happonen L, Knee KM, Janz JM, Steyaert J, Bulawa C, Paavilainen VO, Huiskonen JT, Yue WW. Kelly JJ, et al. Among authors: kramer h. Nat Struct Mol Biol. 2022 May;29(5):420-429. doi: 10.1038/s41594-022-00755-1. Epub 2022 Apr 21. Nat Struct Mol Biol. 2022. PMID: 35449234 Free PMC article.
Indisulam targets RNA splicing and metabolism to serve as a therapeutic strategy for high-risk neuroblastoma.
Nijhuis A, Sikka A, Yogev O, Herendi L, Balcells C, Ma Y, Poon E, Eckold C, Valbuena GN, Xu Y, Liu Y, da Costa BM, Gruet M, Wickremesinghe C, Benito A, Kramer H, Montoya A, Carling D, Want EJ, Jamin Y, Chesler L, Keun HC. Nijhuis A, et al. Among authors: kramer h. Nat Commun. 2022 Mar 16;13(1):1380. doi: 10.1038/s41467-022-28907-3. Nat Commun. 2022. PMID: 35296644 Free PMC article.
Sugar-Induced Obesity and Insulin Resistance Are Uncoupled from Shortened Survival in Drosophila.
van Dam E, van Leeuwen LAG, Dos Santos E, James J, Best L, Lennicke C, Vincent AJ, Marinos G, Foley A, Buricova M, Mokochinski JB, Kramer HB, Lieb W, Laudes M, Franke A, Kaleta C, Cochemé HM. van Dam E, et al. Cell Metab. 2020 Apr 7;31(4):710-725.e7. doi: 10.1016/j.cmet.2020.02.016. Epub 2020 Mar 19. Cell Metab. 2020. PMID: 32197072 Free PMC article.
1,434 results