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Molecular and Functional Profiling of Gαi as an Intracellular pH Sensor.
Prakash A, Li Z, Chirasani VR, Rasquinha JA, Valentin NH, Hubbard GB, Yin G, Dohlman HG, Campbell SL. Prakash A, et al. Among authors: chirasani vr. Res Sq [Preprint]. 2024 Apr 30:rs.3.rs-4203924. doi: 10.21203/rs.3.rs-4203924/v1. Res Sq. 2024. PMID: 38746411 Free PMC article. Preprint.
Urolithin A analog inhibits castration-resistant prostate cancer by targeting the androgen receptor and its variant, androgen receptor-variant 7.
Chandrasekaran B, Tyagi A, Saran U, Kolluru V, Baby BV, Chirasani VR, Dokholyan NV, Lin JM, Singh A, Sharma AK, Ankem MK, Damodaran C. Chandrasekaran B, et al. Among authors: chirasani vr. Front Pharmacol. 2023 Mar 3;14:1137783. doi: 10.3389/fphar.2023.1137783. eCollection 2023. Front Pharmacol. 2023. PMID: 36937838 Free PMC article.
Oncogenic KRAS G12C: Kinetic and redox characterization of covalent inhibition.
Huynh MV, Parsonage D, Forshaw TE, Chirasani VR, Hobbs GA, Wu H, Lee J, Furdui CM, Poole LB, Campbell SL. Huynh MV, et al. Among authors: chirasani vr. J Biol Chem. 2022 Aug;298(8):102186. doi: 10.1016/j.jbc.2022.102186. Epub 2022 Jun 24. J Biol Chem. 2022. PMID: 35753348 Free PMC article.
Enhanced BRAF engagement by NRAS mutants capable of promoting melanoma initiation.
Murphy BM, Terrell EM, Chirasani VR, Weiss TJ, Lew RE, Holderbaum AM, Dhakal A, Posada V, Fort M, Bodnar MS, Carey LM, Chen M, Burd CJ, Coppola V, Morrison DK, Campbell SL, Burd CE. Murphy BM, et al. Among authors: chirasani vr. Nat Commun. 2022 Jun 7;13(1):3153. doi: 10.1038/s41467-022-30881-9. Nat Commun. 2022. PMID: 35672316 Free PMC article.
Whole proteome mapping of compound-protein interactions.
Chirasani VR, Wang J, Sha C, Raup-Konsavage W, Vrana K, Dokholyan NV. Chirasani VR, et al. Curr Res Chem Biol. 2022;2:100035. doi: 10.1016/j.crchbi.2022.100035. Epub 2022 Sep 12. Curr Res Chem Biol. 2022. PMID: 38125869 Free PMC article.
Functional Gly297Ser Variant of the Physiological Dysglycemic Peptide Pancreastatin Is a Novel Risk Factor for Cardiometabolic Disorders.
Allu PKR, Kiranmayi M, Mukherjee SD, Chirasani VR, Garg R, Vishnuprabu D, Ravi S, Subramanian L, Sahu BS, Iyer DR, Maghajothi S, Sharma S, Ravi MS, Khullar M, Munirajan AK, Gayen JR, Senapati S, Mullasari AS, Mohan V, Radha V, Naga Prasad SV, Mahapatra NR. Allu PKR, et al. Among authors: chirasani vr. Diabetes. 2022 Mar 1;71(3):538-553. doi: 10.2337/db21-0289. Diabetes. 2022. PMID: 34862200
34 results