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Antidrug antibodies against the polyethylene glycol moiety inhibit the procoagulant activity of therapeutic polyethylene glycolated factor VIII.
J Thromb Haemost. 2023 Jun;21(6):1503-1514. doi: 10.1016/j.jtha.2023.03.011. Epub 2023 Mar 18.
J Thromb Haemost. 2023.
PMID: 36934798
Free article.
An in silico and in vitro approach to elucidate the impact of residues flanking the cleavage scissile bonds of FVIII.
Pezeshkpoor B, Schreck U, Biswas A, Driesen J, Berkemeier AC, Pavlova A, Müller J, Oldenburg J.
Pezeshkpoor B, et al. Among authors: berkemeier ac.
PLoS One. 2017 Jul 6;12(7):e0180456. doi: 10.1371/journal.pone.0180456. eCollection 2017.
PLoS One. 2017.
PMID: 28683085
Free PMC article.
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Variants in FIX propeptide associated with vitamin K antagonist hypersensitivity: functional analysis and additional data confirming the common founder mutations.
Pezeshkpoor B, Czogalla KJ, Caspers M, Berkemeier AC, Liphardt K, Ghosh S, Kellner M, Ulrich S, Pavlova A, Oldenburg J.
Pezeshkpoor B, et al. Among authors: berkemeier ac.
Ann Hematol. 2018 Jun;97(6):1061-1069. doi: 10.1007/s00277-018-3264-2. Epub 2018 Feb 15.
Ann Hematol. 2018.
PMID: 29450643
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Comprehensive domain-specific analysis and immunoglobulin G profiling of anti-factor VIII antibodies using a bead-based multiplex immunoassay.
Pezeshkpoor B, Berkemeier AC, Herbst K, Albert T, Müller J, Oldenburg J.
Pezeshkpoor B, et al. Among authors: berkemeier ac.
J Thromb Haemost. 2024 Jun;22(6):1591-1604. doi: 10.1016/j.jtha.2024.02.016. Epub 2024 Mar 5.
J Thromb Haemost. 2024.
PMID: 38453023
Free article.
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In silico and in vitro evaluation of the impact of mutations in non-severe haemophilia A patients on assay discrepancies.
Pezeshkpoor B, Gazorpak M, Berkemeier AC, Singer H, Pavlova A, Biswas A, Oldenburg J.
Pezeshkpoor B, et al. Among authors: berkemeier ac.
Ann Hematol. 2019 Aug;98(8):1855-1865. doi: 10.1007/s00277-019-03691-1. Epub 2019 Apr 17.
Ann Hematol. 2019.
PMID: 30997536
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Evidence of pathogenicity of a mutation in 3' untranslated region causing mild haemophilia A.
Pezeshkpoor B, Berkemeier AC, Czogalla KJ, Oldenburg J, El-Maarri O.
Pezeshkpoor B, et al. Among authors: berkemeier ac.
Haemophilia. 2016 Jul;22(4):598-603. doi: 10.1111/hae.12923. Epub 2016 May 24.
Haemophilia. 2016.
PMID: 27216882
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