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IFNγ-induction of TH1-like regulatory T cells controls antiviral responses.
Gocher-Demske AM, Cui J, Szymczak-Workman AL, Vignali KM, Latini JN, Pieklo GP, Kimball JC, Avery L, Cipolla EM, Huckestein BR, Hedden L, Meisel M, Alcorn JF, Kane LP, Workman CJ, Vignali DAA. Gocher-Demske AM, et al. Among authors: vignali km. Nat Immunol. 2023 May;24(5):841-854. doi: 10.1038/s41590-023-01453-w. Epub 2023 Mar 16. Nat Immunol. 2023. PMID: 36928412 Free PMC article.
The inhibitory cytokine IL-35 contributes to regulatory T-cell function.
Collison LW, Workman CJ, Kuo TT, Boyd K, Wang Y, Vignali KM, Cross R, Sehy D, Blumberg RS, Vignali DA. Collison LW, et al. Among authors: vignali da, vignali km. Nature. 2007 Nov 22;450(7169):566-9. doi: 10.1038/nature06306. Nature. 2007. PMID: 18033300
LAG3 limits regulatory T cell proliferation and function in autoimmune diabetes.
Zhang Q, Chikina M, Szymczak-Workman AL, Horne W, Kolls JK, Vignali KM, Normolle D, Bettini M, Workman CJ, Vignali DAA. Zhang Q, et al. Among authors: vignali km. Sci Immunol. 2017 Mar 31;2(9):eaah4569. doi: 10.1126/sciimmunol.aah4569. Sci Immunol. 2017. PMID: 28783703 Free PMC article.
Neuropilin-1 is a T cell memory checkpoint limiting long-term antitumor immunity.
Liu C, Somasundaram A, Manne S, Gocher AM, Szymczak-Workman AL, Vignali KM, Scott EN, Normolle DP, John Wherry E, Lipson EJ, Ferris RL, Bruno TC, Workman CJ, Vignali DAA. Liu C, et al. Among authors: vignali km. Nat Immunol. 2020 Sep;21(9):1010-1021. doi: 10.1038/s41590-020-0733-2. Epub 2020 Jul 13. Nat Immunol. 2020. PMID: 32661362 Free PMC article.
Epitope Mapping of Therapeutic Antibodies Targeting Human LAG3.
Agnihotri P, Mishra AK, Agarwal P, Vignali KM, Workman CJ, Vignali DAA, Mariuzza RA. Agnihotri P, et al. Among authors: vignali km. J Immunol. 2022 Oct 15;209(8):1586-1594. doi: 10.4049/jimmunol.2200309. Epub 2022 Sep 14. J Immunol. 2022. PMID: 36104110 Free PMC article.
The composition and signaling of the IL-35 receptor are unconventional.
Collison LW, Delgoffe GM, Guy CS, Vignali KM, Chaturvedi V, Fairweather D, Satoskar AR, Garcia KC, Hunter CA, Drake CG, Murray PJ, Vignali DA. Collison LW, et al. Among authors: vignali da, vignali km. Nat Immunol. 2012 Feb 5;13(3):290-9. doi: 10.1038/ni.2227. Nat Immunol. 2012. PMID: 22306691 Free PMC article.
A Cre-driven allele-conditioning line to interrogate CD4+ conventional T cells.
Andrews LP, Vignali KM, Szymczak-Workman AL, Burton AR, Brunazzi EA, Ngiow SF, Harusato A, Sharpe AH, Wherry EJ, Taniuchi I, Workman CJ, Vignali DAA. Andrews LP, et al. Among authors: vignali km. Immunity. 2021 Oct 12;54(10):2209-2217.e6. doi: 10.1016/j.immuni.2021.08.029. Epub 2021 Sep 21. Immunity. 2021. PMID: 34551314 Free article.
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