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SPOC domain proteins in health and disease.
Genes Dev. 2023 Mar 1;37(5-6):140-170. doi: 10.1101/gad.350314.122. Epub 2023 Mar 16.
Genes Dev. 2023.
PMID: 36927757
Free PMC article.
Review.
PHF3 regulates neuronal gene expression through the Pol II CTD reader domain SPOC.
Appel LM, Franke V, Bruno M, Grishkovskaya I, Kasiliauskaite A, Kaufmann T, Schoeberl UE, Puchinger MG, Kostrhon S, Ebenwaldner C, Sebesta M, Beltzung E, Mechtler K, Lin G, Vlasova A, Leeb M, Pavri R, Stark A, Akalin A, Stefl R, Bernecky C, Djinovic-Carugo K, Slade D.
Appel LM, et al.
Nat Commun. 2021 Oct 19;12(1):6078. doi: 10.1038/s41467-021-26360-2.
Nat Commun. 2021.
PMID: 34667177
Free PMC article.
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The SPOC domain is a phosphoserine binding module that bridges transcription machinery with co- and post-transcriptional regulators.
Appel LM, Franke V, Benedum J, Grishkovskaya I, Strobl X, Polyansky A, Ammann G, Platzer S, Neudolt A, Wunder A, Walch L, Kaiser S, Zagrovic B, Djinovic-Carugo K, Akalin A, Slade D.
Appel LM, et al.
Nat Commun. 2023 Jan 11;14(1):166. doi: 10.1038/s41467-023-35853-1.
Nat Commun. 2023.
PMID: 36631525
Free PMC article.
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The SPOC proteins DIDO3 and PHF3 co-regulate gene expression and neuronal differentiation.
Benedum J, Franke V, Appel LM, Walch L, Bruno M, Schneeweiss R, Gruber J, Oberndorfer H, Frank E, Strobl X, Polyansky A, Zagrovic B, Akalin A, Slade D.
Benedum J, et al. Among authors: appel lm.
Nat Commun. 2023 Nov 30;14(1):7912. doi: 10.1038/s41467-023-43724-y.
Nat Commun. 2023.
PMID: 38036524
Free PMC article.
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The Outcome of Ex Vivo TIL Expansion Is Highly Influenced by Spatial Heterogeneity of the Tumor T-Cell Repertoire and Differences in Intrinsic In Vitro Growth Capacity between T-Cell Clones.
Poschke IC, Hassel JC, Rodriguez-Ehrenfried A, Lindner KAM, Heras-Murillo I, Appel LM, Lehmann J, Lövgren T, Wickström SL, Lauenstein C, Roth J, König AK, Haanen JBAG, van den Berg J, Kiessling R, Bergmann F, Flossdorf M, Strobel O, Offringa R.
Poschke IC, et al. Among authors: appel lm.
Clin Cancer Res. 2020 Aug 15;26(16):4289-4301. doi: 10.1158/1078-0432.CCR-19-3845. Epub 2020 Apr 17.
Clin Cancer Res. 2020.
PMID: 32303540
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Cerebral arterial ectasia with vertebral aneurysm.
Appel LM, Baeck E.
Appel LM, et al.
J Belge Radiol. 1981;64(5):415-20.
J Belge Radiol. 1981.
PMID: 7343555
No abstract available.
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