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Preclinical safety and efficacy of a therapeutic antibody that targets SARS-CoV-2 at the sotrovimab face but is escaped by Omicron.
Kreye J, Reincke SM, Edelburg S, Jeworowski LM, Kornau HC, Trimpert J, Hombach P, Halbe S, Nölle V, Meyer M, Kattenbach S, Sánchez-Sendin E, Schmidt ML, Schwarz T, Rose R, Krumbholz A, Merz S, Adler JM, Eschke K, Abdelgawad A, Schmitz D, Sander LE, Janssen U, Corman VM, Prüss H. Kreye J, et al. iScience. 2023 Apr 21;26(4):106323. doi: 10.1016/j.isci.2023.106323. Epub 2023 Mar 2. iScience. 2023. PMID: 36925720 Free PMC article.
Human cerebrospinal fluid monoclonal N-methyl-D-aspartate receptor autoantibodies are sufficient for encephalitis pathogenesis.
Kreye J, Wenke NK, Chayka M, Leubner J, Murugan R, Maier N, Jurek B, Ly LT, Brandl D, Rost BR, Stumpf A, Schulz P, Radbruch H, Hauser AE, Pache F, Meisel A, Harms L, Paul F, Dirnagl U, Garner C, Schmitz D, Wardemann H, Prüss H. Kreye J, et al. Brain. 2016 Oct;139(Pt 10):2641-2652. doi: 10.1093/brain/aww208. Epub 2016 Aug 20. Brain. 2016. PMID: 27543972
N-methyl-D-aspartate receptor dysfunction by unmutated human antibodies against the NR1 subunit.
Wenke NK, Kreye J, Andrzejak E, van Casteren A, Leubner J, Murgueitio MS, Reincke SM, Secker C, Schmidl L, Geis C, Ackermann F, Nikolaus M, Garner CC, Wardemann H, Wolber G, Prüss H. Wenke NK, et al. Among authors: kreye j. Ann Neurol. 2019 May;85(5):771-776. doi: 10.1002/ana.25460. Epub 2019 Apr 2. Ann Neurol. 2019. PMID: 30843274 Free PMC article.
Human gestational N-methyl-d-aspartate receptor autoantibodies impair neonatal murine brain function.
Jurek B, Chayka M, Kreye J, Lang K, Kraus L, Fidzinski P, Kornau HC, Dao LM, Wenke NK, Long M, Rivalan M, Winter Y, Leubner J, Herken J, Mayer S, Mueller S, Boehm-Sturm P, Dirnagl U, Schmitz D, Kölch M, Prüss H. Jurek B, et al. Among authors: kreye j. Ann Neurol. 2019 Nov;86(5):656-670. doi: 10.1002/ana.25552. Epub 2019 Sep 18. Ann Neurol. 2019. PMID: 31325344
IgA autoantibodies against native myelin basic protein in a patient with MS.
Schumacher H, Wenke NK, Kreye J, Höltje M, Marcus K, May C, Prüss H. Schumacher H, et al. Among authors: kreye j. Neurol Neuroimmunol Neuroinflamm. 2019 May 1;6(4):e569. doi: 10.1212/NXI.0000000000000569. eCollection 2019 Jul. Neurol Neuroimmunol Neuroinflamm. 2019. PMID: 31355305 Free PMC article. No abstract available.
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