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Myeloid cells from Langerhans cell histiocytosis patients exhibit increased vesicle trafficking and an altered secretome capable of activating NK cells.
Hagey DW, Kvedaraite E, Akber M, Görgens A, Javadi J, Von Bahr Greenwood T, Björklund C, Åkefeldt SO, Hannegård-Hamrin T, Arnell H, Dobra K, Herold N, Svensson M, El Andaloussi S, Henter JI, Lourda M. Hagey DW, et al. Among authors: akefeldt so. Haematologica. 2023 Sep 1;108(9):2422-2434. doi: 10.3324/haematol.2022.282638. Haematologica. 2023. PMID: 36924254 Free PMC article.
Patients with both Langerhans cell histiocytosis and Crohn's disease highlight a common role of interleukin-23.
Kvedaraite E, Lourda M, Han H, Tesi B, Mitchell J, Ideström M, Mouratidou N, Rassidakis G, von Bahr Greenwood T, Cohen-Aubart F, Jädersten M, Åkefeldt SO, Svensson M, Kannourakis G, Bryceson YT, Haroche J, Henter JI. Kvedaraite E, et al. Among authors: akefeldt so. Acta Paediatr. 2021 Apr;110(4):1315-1321. doi: 10.1111/apa.15590. Epub 2020 Oct 8. Acta Paediatr. 2021. PMID: 32975844 Free PMC article.
Polyclonal T-cells express CD1a in Langerhans cell histiocytosis (LCH) lesions.
West JA, Olsen SL, Mitchell JM, Priddle RE, Luke JM, Akefeldt SO, Henter JI, Turville C, Kannourakis G. West JA, et al. Among authors: akefeldt so. PLoS One. 2014 Oct 24;9(10):e109586. doi: 10.1371/journal.pone.0109586. eCollection 2014. PLoS One. 2014. PMID: 25343480 Free PMC article.