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First-in-class small molecule inhibitors of the single-strand DNA cytosine deaminase APOBEC3G.
Li M, Shandilya SM, Carpenter MA, Rathore A, Brown WL, Perkins AL, Harki DA, Solberg J, Hook DJ, Pandey KK, Parniak MA, Johnson JR, Krogan NJ, Somasundaran M, Ali A, Schiffer CA, Harris RS. Li M, et al. Among authors: carpenter ma. ACS Chem Biol. 2012 Mar 16;7(3):506-17. doi: 10.1021/cb200440y. Epub 2012 Jan 17. ACS Chem Biol. 2012. PMID: 22181350 Free PMC article.
Determinants of Oligonucleotide Selectivity of APOBEC3B.
Wagner JR, Demir Ö, Carpenter MA, Aihara H, Harki DA, Harris RS, Amaro RE. Wagner JR, et al. Among authors: carpenter ma. J Chem Inf Model. 2019 May 28;59(5):2264-2273. doi: 10.1021/acs.jcim.8b00427. Epub 2018 Sep 10. J Chem Inf Model. 2019. PMID: 30130104 Free PMC article.
Structural basis for recognition of distinct deaminated DNA lesions by endonuclease Q.
Shi K, Moeller NH, Banerjee S, McCann JL, Carpenter MA, Yin L, Moorthy R, Orellana K, Harki DA, Harris RS, Aihara H. Shi K, et al. Among authors: carpenter ma. Proc Natl Acad Sci U S A. 2021 Mar 9;118(10):e2021120118. doi: 10.1073/pnas.2021120118. Proc Natl Acad Sci U S A. 2021. PMID: 33658373 Free PMC article.
Structural Characterization of a Minimal Antibody against Human APOBEC3B.
Tang H, Demir Ö, Kurniawan F, Brown WL, Shi K, Moeller NH, Carpenter MA, Belica C, Orellana K, Du G, LeBeau AM, Amaro RE, Harris RS, Aihara H. Tang H, et al. Among authors: carpenter ma. Viruses. 2021 Apr 12;13(4):663. doi: 10.3390/v13040663. Viruses. 2021. PMID: 33921405 Free PMC article.
242 results