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Neoadjuvant immune checkpoint blockade triggers persistent and systemic Treg activation which blunts therapeutic efficacy against metastatic spread of breast tumors.
Oncoimmunology. 2023 Apr 13;12(1):2201147. doi: 10.1080/2162402X.2023.2201147. eCollection 2023.
Oncoimmunology. 2023.
PMID: 37089449
Free PMC article.
Tumor-expressed factor VII is associated with survival and regulates tumor progression in breast cancer.
Kroone C, Tieken C, Kocatürk B, Paauwe M, Blok EJ, Ünlü B, van den Berg YW, Stanganello E, Kapteijn MY, Swier N, Zhang X, Duits DEM, Lin Y, Oostenbrink LVE, van den Akker RFP, Mosnier LO, Hawinkels LJ, van Vlijmen BJM, Ruf W, Kuppen PJ, Cannegieter SC, Buijs JT, Versteeg HH.
Kroone C, et al. Among authors: duits dem.
Blood Adv. 2023 Jun 13;7(11):2388-2400. doi: 10.1182/bloodadvances.2022008455.
Blood Adv. 2023.
PMID: 36920782
Free PMC article.
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hMRP8-ATTAC Mice: A New Model for Conditional and Reversible Neutrophil Ablation.
Duits DEM, Salvagno C, Raeven EAM, Vrijland K, Stip MC, Hau CS, Kaldenbach D, de Visser KE.
Duits DEM, et al.
Cells. 2022 Jul 30;11(15):2346. doi: 10.3390/cells11152346.
Cells. 2022.
PMID: 35954190
Free PMC article.
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Tumor-educated Tregs drive organ-specific metastasis in breast cancer by impairing NK cells in the lymph node niche.
Kos K, Aslam MA, van de Ven R, Wellenstein MD, Pieters W, van Weverwijk A, Duits DEM, van Pul K, Hau CS, Vrijland K, Kaldenbach D, Raeven EAM, Quezada SA, Beyaert R, Jacobs H, de Gruijl TD, de Visser KE.
Kos K, et al. Among authors: duits dem.
Cell Rep. 2022 Mar 1;38(9):110447. doi: 10.1016/j.celrep.2022.110447.
Cell Rep. 2022.
PMID: 35235800
Free article.
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Impact of cancer cell-intrinsic features on neutrophil behavior.
Duits DEM, de Visser KE.
Duits DEM, et al.
Semin Immunol. 2021 Oct;57:101546. doi: 10.1016/j.smim.2021.101546. Epub 2021 Dec 7.
Semin Immunol. 2021.
PMID: 34887163
Free article.
Review.
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In vitro assessment of cancer cell-induced polarization of macrophages.
Duits DEM, Wellenstein MD, de Visser KE.
Duits DEM, et al.
Methods Enzymol. 2020;632:133-154. doi: 10.1016/bs.mie.2019.06.011. Epub 2019 Jul 13.
Methods Enzymol. 2020.
PMID: 32000893
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Loss of p53 triggers WNT-dependent systemic inflammation to drive breast cancer metastasis.
Wellenstein MD, Coffelt SB, Duits DEM, van Miltenburg MH, Slagter M, de Rink I, Henneman L, Kas SM, Prekovic S, Hau CS, Vrijland K, Drenth AP, de Korte-Grimmerink R, Schut E, van der Heijden I, Zwart W, Wessels LFA, Schumacher TN, Jonkers J, de Visser KE.
Wellenstein MD, et al. Among authors: duits dem.
Nature. 2019 Aug;572(7770):538-542. doi: 10.1038/s41586-019-1450-6. Epub 2019 Jul 31.
Nature. 2019.
PMID: 31367040
Free PMC article.
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Loss of MAPK Pathway Activation in Post-Mitotic Retinal Cells as Mechanism in MEK Inhibition-Related Retinopathy in Cancer Patients.
van Dijk EHC, Duits DEM, Versluis M, Luyten GPM, Bergen AAB, Kapiteijn EW, de Lange MJ, Boon CJF, van der Velden PA.
van Dijk EHC, et al. Among authors: duits dem.
Medicine (Baltimore). 2016 May;95(18):e3457. doi: 10.1097/MD.0000000000003457.
Medicine (Baltimore). 2016.
PMID: 27149444
Free PMC article.
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