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Fibroblast-derived EGF ligand neuregulin 1 induces fetal-like reprogramming of the intestinal epithelium without supporting tumorigenic growth.
Dis Model Mech. 2023 Apr 1;16(4):dmm049692. doi: 10.1242/dmm.049692. Epub 2023 Apr 3.
Dis Model Mech. 2023.
PMID: 36912192
Free PMC article.
Tellu - an object-detector algorithm for automatic classification of intestinal organoids.
Domènech-Moreno E, Brandt A, Lemmetyinen TT, Wartiovaara L, Mäkelä TP, Ollila S.
Domènech-Moreno E, et al.
Dis Model Mech. 2023 Mar 1;16(3):dmm049756. doi: 10.1242/dmm.049756. Epub 2023 Mar 13.
Dis Model Mech. 2023.
PMID: 36804687
Free PMC article.
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Inactivation of AMPK Leads to Attenuation of Antigen Presentation and Immune Evasion in Lung Adenocarcinoma.
Gao Y, Päivinen P, Tripathi S, Domènech-Moreno E, Wong IPL, Vaahtomeri K, Nagaraj AS, Talwelkar SS, Foretz M, Verschuren EW, Viollet B, Yan Y, Mäkelä TP.
Gao Y, et al. Among authors: domenech moreno e.
Clin Cancer Res. 2022 Jan 1;28(1):227-237. doi: 10.1158/1078-0432.CCR-21-2049. Epub 2021 Oct 19.
Clin Cancer Res. 2022.
PMID: 34667030
Free article.
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LKB1 Represses ATOH1 via PDK4 and Energy Metabolism and Regulates Intestinal Stem Cell Fate.
Gao Y, Yan Y, Tripathi S, Pentinmikko N, Amaral A, Päivinen P, Domènech-Moreno E, Andersson S, Wong IPL, Clevers H, Katajisto P, Mäkelä TP.
Gao Y, et al. Among authors: domenech moreno e.
Gastroenterology. 2020 Apr;158(5):1389-1401.e10. doi: 10.1053/j.gastro.2019.12.033. Epub 2020 Jan 11.
Gastroenterology. 2020.
PMID: 31930988
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Depletion of Mediator Kinase Module Subunits Represses Superenhancer-Associated Genes in Colon Cancer Cells.
Kuuluvainen E, Domènech-Moreno E, Niemelä EH, Mäkelä TP.
Kuuluvainen E, et al. Among authors: domenech moreno e.
Mol Cell Biol. 2018 May 15;38(11):e00573-17. doi: 10.1128/MCB.00573-17. Print 2018 Jun 1.
Mol Cell Biol. 2018.
PMID: 29507187
Free PMC article.
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Stromal Lkb1 deficiency leads to gastrointestinal tumorigenesis involving the IL-11-JAK/STAT3 pathway.
Ollila S, Domènech-Moreno E, Laajanen K, Wong IP, Tripathi S, Pentinmikko N, Gao Y, Yan Y, Niemelä EH, Wang TC, Viollet B, Leone G, Katajisto P, Vaahtomeri K, Mäkelä TP.
Ollila S, et al. Among authors: domenech moreno e.
J Clin Invest. 2018 Jan 2;128(1):402-414. doi: 10.1172/JCI93597. Epub 2017 Dec 4.
J Clin Invest. 2018.
PMID: 29202476
Free PMC article.
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