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Histone H3 serotonylation dynamics in dorsal raphe nucleus contribute to stress- and antidepressant-mediated gene expression and behavior.
Al-Kachak A, Fulton SL, Di Salvo G, Chan JC, Farrelly LA, Lepack AE, Bastle RM, Kong L, Cathomas F, Newman EL, Menard C, Ramakrishnan A, Safovich P, Lyu Y, Covington HE 3rd, Shen L, Gleason K, Tamminga CA, Russo SJ, Maze I. Al-Kachak A, et al. Among authors: maze i. bioRxiv [Preprint]. 2023 Sep 16:2023.05.04.539464. doi: 10.1101/2023.05.04.539464. bioRxiv. 2023. PMID: 37205414 Free PMC article. Preprint.
ZBTB7A regulates MDD-specific chromatin signatures and astrocyte-mediated stress vulnerability in orbitofrontal cortex.
Fulton SL, Bendl J, Gameiro-Ros I, Fullard JF, Al-Kachak A, Lepack AE, Stewart AF, Singh S, Poller WC, Bastle RM, Hauberg ME, Fakira AK, Chen M, Cuttoli RD, Cathomas F, Ramakrishnan A, Gleason K, Shen L, Tamminga CA, Milosevic A, Russo SJ, Swirski F, Blitzer RD, Slesinger PA, Roussos P, Maze I. Fulton SL, et al. Among authors: maze i. bioRxiv [Preprint]. 2023 May 4:2023.05.04.539425. doi: 10.1101/2023.05.04.539425. bioRxiv. 2023. PMID: 37205394 Free PMC article. Preprint.
Dissociable contributions of the amygdala and ventral hippocampus to stress-induced changes in defensive behavior.
Pennington ZT, LaBanca AR, Sompolpong P, Abdel-Raheim SD, Ko B, Christenson Wick Z, Feng Y, Dong Z, Francisco TR, Bacon ME, Chen L, Fulton SL, Maze I, Shuman T, Cai DJ. Pennington ZT, et al. Among authors: maze i. bioRxiv [Preprint]. 2024 May 8:2023.02.27.530077. doi: 10.1101/2023.02.27.530077. bioRxiv. 2024. PMID: 36945605 Free PMC article. Preprint.
Flexible and site-specific manipulation of histones in live animals.
Finkin-Groner E, Al-Kachak A, Agustinus A, Bastle R, Lepack A, Lyu Y, Maze I, David Y. Finkin-Groner E, et al. Among authors: maze i. bioRxiv [Preprint]. 2023 Mar 20:2023.03.19.533378. doi: 10.1101/2023.03.19.533378. bioRxiv. 2023. PMID: 36993231 Free PMC article. Preprint.
Histone serotonylation is a permissive modification that enhances TFIID binding to H3K4me3.
Farrelly LA, Thompson RE, Zhao S, Lepack AE, Lyu Y, Bhanu NV, Zhang B, Loh YE, Ramakrishnan A, Vadodaria KC, Heard KJ, Erikson G, Nakadai T, Bastle RM, Lukasak BJ, Zebroski H 3rd, Alenina N, Bader M, Berton O, Roeder RG, Molina H, Gage FH, Shen L, Garcia BA, Li H, Muir TW, Maze I. Farrelly LA, et al. Among authors: maze i. Nature. 2019 Mar;567(7749):535-539. doi: 10.1038/s41586-019-1024-7. Epub 2019 Mar 13. Nature. 2019. PMID: 30867594 Free PMC article.
73 results