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Initiation and modulation of Tau protein phase separation by the drug suramin.
Sci Rep. 2023 Mar 9;13(1):3963. doi: 10.1038/s41598-023-29846-9.
Sci Rep. 2023.
PMID: 36894559
Free PMC article.
Light Microscopy and Dynamic Light Scattering to Study Liquid-Liquid Phase Separation of Tau Proteins In Vitro.
Hochmair J, Exner C, Betzel C, Mandelkow E, Wegmann S.
Hochmair J, et al.
Methods Mol Biol. 2023;2551:225-243. doi: 10.1007/978-1-0716-2597-2_15.
Methods Mol Biol. 2023.
PMID: 36310206
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Phosphorylation but Not Oligomerization Drives the Accumulation of Tau with Nucleoporin Nup98.
Diez L, Kapinos LE, Hochmair J, Huebschmann S, Dominguez-Baquero A, Vogt A, Rankovic M, Zweckstetter M, Lim RYH, Wegmann S.
Diez L, et al. Among authors: hochmair j.
Int J Mol Sci. 2022 Mar 23;23(7):3495. doi: 10.3390/ijms23073495.
Int J Mol Sci. 2022.
PMID: 35408855
Free PMC article.
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Molecular crowding and RNA synergize to promote phase separation, microtubule interaction, and seeding of Tau condensates.
Hochmair J, Exner C, Franck M, Dominguez-Baquero A, Diez L, Brognaro H, Kraushar ML, Mielke T, Radbruch H, Kaniyappan S, Falke S, Mandelkow E, Betzel C, Wegmann S.
Hochmair J, et al.
EMBO J. 2022 Jun 1;41(11):e108882. doi: 10.15252/embj.2021108882. Epub 2022 Mar 17.
EMBO J. 2022.
PMID: 35298090
Free PMC article.
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Bap (Sil1) regulates the molecular chaperone BiP by coupling release of nucleotide and substrate.
Rosam M, Krader D, Nickels C, Hochmair J, Back KC, Agam G, Barth A, Zeymer C, Hendrix J, Schneider M, Antes I, Reinstein J, Lamb DC, Buchner J.
Rosam M, et al. Among authors: hochmair j.
Nat Struct Mol Biol. 2018 Jan;25(1):90-100. doi: 10.1038/s41594-017-0012-6. Epub 2018 Jan 1.
Nat Struct Mol Biol. 2018.
PMID: 29323281
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