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Morphology-guided transcriptomic analysis of human pancreatic cancer organoids reveals microenvironmental signals that enhance invasion.
Jeong YJ, Knutsdottir H, Shojaeian F, Lerner MG, Wissler MF, Henriet E, Ng T, Datta S, Navarro-Serer B, Chianchiano P, Kinny-Köster B, Zimmerman JW, Stein-O'Brien G, Gaida MM, Eshleman JR, Lin MT, Fertig EJ, Ewald AJ, Bader JS, Wood LD. Jeong YJ, et al. Among authors: bader js. J Clin Invest. 2023 Apr 17;133(8):e162054. doi: 10.1172/JCI162054. J Clin Invest. 2023. PMID: 36881486 Free PMC article.
Ensemble Detection of DNA Engineering Signatures.
Adler A, Bader JS, Basnight B, Booth BW, Cai J, Cho E, Collins JH, Ge Y, Grothendieck J, Keating K, Marshall T, Persikov A, Scott H, Siegelmann R, Singh M, Taggart A, Toll B, Wan KH, Wyschogrod D, Yaman F, Young EM, Celniker SE, Roehner N. Adler A, et al. Among authors: bader js. ACS Synth Biol. 2024 Apr 19;13(4):1105-1115. doi: 10.1021/acssynbio.3c00398. Epub 2024 Mar 12. ACS Synth Biol. 2024. PMID: 38468602
Proteomic Signature of HIV-Associated Subclinical Left Atrial Remodeling and Incident Heart Failure.
Peterson TE, Hahn VS, Moaddel R, Zhu M, Haberlen SA, Palella FJ, Plankey M, Bader JS, Lima JA, Gerszten RE, Rotter JI, Rich SS, Heckbert SR, Kirk GD, Piggott DA, Ferrucci L, Margolick JB, Brown TT, Wu KC, Post WS. Peterson TE, et al. Among authors: bader js. medRxiv [Preprint]. 2024 Feb 14:2024.02.13.24302797. doi: 10.1101/2024.02.13.24302797. medRxiv. 2024. PMID: 38405757 Free PMC article. Preprint.
Parallel laboratory evolution and rational debugging reveal genomic plasticity to S. cerevisiae synthetic chromosome XIV defects.
Williams TC, Kroukamp H, Xu X, Wightman ELI, Llorente B, Borneman AR, Carpenter AC, Van Wyk N, Meier F, Collier TRV, Espinosa MI, Daniel EL, Walker RSK, Cai Y, Nevalainen HKM, Curach NC, Deveson IW, Mercer TR, Johnson DL, Mitchell LA, Bader JS, Stracquadanio G, Boeke JD, Goold HD, Pretorius IS, Paulsen IT. Williams TC, et al. Among authors: bader js. Cell Genom. 2023 Nov 9;3(11):100379. doi: 10.1016/j.xgen.2023.100379. eCollection 2023 Nov 8. Cell Genom. 2023. PMID: 38020977 Free PMC article.
Consequences of a telomerase-related fitness defect and chromosome substitution technology in yeast synIX strains.
McCulloch LH, Sambasivam V, Hughes AL, Annaluru N, Ramalingam S, Fanfani V, Lobzaev E, Mitchell LA, Cai J; Build-A-Genome Class; Jiang H, LaCava J, Taylor MS, Bishai WR, Stracquadanio G, Steinmetz LM, Bader JS, Zhang W, Boeke JD, Chandrasegaran S. McCulloch LH, et al. Among authors: bader js. Cell Genom. 2023 Nov 9;3(11):100419. doi: 10.1016/j.xgen.2023.100419. eCollection 2023 Nov 8. Cell Genom. 2023. PMID: 38020974 Free PMC article.
Synthetic yeast chromosome XI design provides a testbed for the study of extrachromosomal circular DNA dynamics.
Blount BA, Lu X, Driessen MRM, Jovicevic D, Sanchez MI, Ciurkot K, Zhao Y, Lauer S, McKiernan RM, Gowers GF, Sweeney F, Fanfani V, Lobzaev E, Palacios-Flores K, Walker RSK, Hesketh A, Cai J, Oliver SG, Cai Y, Stracquadanio G, Mitchell LA, Bader JS, Boeke JD, Ellis T. Blount BA, et al. Among authors: bader js. Cell Genom. 2023 Nov 9;3(11):100418. doi: 10.1016/j.xgen.2023.100418. eCollection 2023 Nov 8. Cell Genom. 2023. PMID: 38020971 Free PMC article.
Establishing chromosomal design-build-test-learn through a synthetic chromosome and its combinatorial reconfiguration.
Foo JL, Kitano S, Susanto AV, Jin Z, Lin Y, Luo Z, Huang L, Liang Z, Mitchell LA, Yang K, Wong A, Cai Y, Cai J, Stracquadanio G, Bader JS, Boeke JD, Dai J, Chang MW. Foo JL, et al. Among authors: bader js. Cell Genom. 2023 Nov 9;3(11):100435. doi: 10.1016/j.xgen.2023.100435. eCollection 2023 Nov 8. Cell Genom. 2023. PMID: 38020970 Free PMC article.
141 results