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Fungal biotransformation of tanshinone results in [4+2] cycloaddition with sorbicillinol: evidence for enzyme catalysis and increased antibacterial activity.
He W, Liu M, Li X, Zhang X, Abdel-Mageed WM, Li L, Wang W, Zhang J, Han J, Dai H, Quinn RJ, Liu HW, Luo H, Zhang L, Liu X. He W, et al. Among authors: zhang l, zhang j, zhang x. Appl Microbiol Biotechnol. 2016 Oct;100(19):8349-57. doi: 10.1007/s00253-016-7488-6. Epub 2016 May 20. Appl Microbiol Biotechnol. 2016. PMID: 27198724
Discovery of tanshinone derivatives with anti-MRSA activity via targeted bio-transformation.
He W, Liu M, Huang P, Abdel-Mageed WM, Han J, Watrous JD, Nguyen DD, Wang W, Song F, Dai H, Zhang J, Quinn RJ, Grkovi T, Luo H, Zhang L, Liu X. He W, et al. Among authors: zhang l, zhang j. Synth Syst Biotechnol. 2016 Jul 1;1(3):187-194. doi: 10.1016/j.synbio.2016.05.002. eCollection 2016 Sep. Synth Syst Biotechnol. 2016. PMID: 29062942 Free PMC article.
Genome- and MS-based mining of antibacterial chlorinated chromones and xanthones from the phytopathogenic fungus Bipolaris sorokiniana strain 11134.
Han J, Zhang J, Song Z, Liu M, Hu J, Hou C, Zhu G, Jiang L, Xia X, Quinn RJ, Feng Y, Zhang L, Hsiang T, Liu X. Han J, et al. Among authors: zhang l, zhang j. Appl Microbiol Biotechnol. 2019 Jul;103(13):5167-5181. doi: 10.1007/s00253-019-09821-z. Epub 2019 Apr 19. Appl Microbiol Biotechnol. 2019. PMID: 31001746
A CRISPR-Cas12a-derived biosensing platform for the highly sensitive detection of diverse small molecules.
Liang M, Li Z, Wang W, Liu J, Liu L, Zhu G, Karthik L, Wang M, Wang KF, Wang Z, Yu J, Shuai Y, Yu J, Zhang L, Yang Z, Li C, Zhang Q, Shi T, Zhou L, Xie F, Dai H, Liu X, Zhang J, Liu G, Zhuo Y, Zhang B, Liu C, Li S, Xia X, Tong Y, Liu Y, Alterovitz G, Tan GY, Zhang LX. Liang M, et al. Among authors: zhang l, zhang b, zhang q, zhang lx, zhang j. Nat Commun. 2019 Aug 14;10(1):3672. doi: 10.1038/s41467-019-11648-1. Nat Commun. 2019. PMID: 31413315 Free PMC article.
Harnessing the intracellular triacylglycerols for titer improvement of polyketides in Streptomyces.
Wang W, Li S, Li Z, Zhang J, Fan K, Tan G, Ai G, Lam SM, Shui G, Yang Z, Lu H, Jin P, Li Y, Chen X, Xia X, Liu X, Dannelly HK, Yang C, Yang Y, Zhang S, Alterovitz G, Xiang W, Zhang L. Wang W, et al. Among authors: zhang l, zhang s, zhang j. Nat Biotechnol. 2020 Jan;38(1):76-83. doi: 10.1038/s41587-019-0335-4. Epub 2019 Dec 9. Nat Biotechnol. 2020. PMID: 31819261
166,189 results
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