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Phase 1 study to determine the safety and dosing of autologous PBMCs modified to present HPV16 antigens (SQZ-PBMC-HPV) in HLA-A*02+ patients with HPV16+ solid tumors.
Jimeno A, Baranda J, Iams WT, Park JC, Mita M, Gordon MS, Taylor M, Dhani N, Leal AD, Neupane P, Eng C, Yeku O, Mita A, Moser JC, Butler M, Loughhead SM, Jennings J, Miselis NR, Ji RR, Nair N, Kornacker M, Zwirtes RF, Bernstein H, Sharei A. Jimeno A, et al. Among authors: gordon ms. Invest New Drugs. 2023 Apr;41(2):284-295. doi: 10.1007/s10637-023-01342-x. Epub 2023 Mar 3. Invest New Drugs. 2023. PMID: 36867316 Free PMC article. Clinical Trial.
Addendum: The value of comprehensive genomic sequencing to maximize the identification of clinically actionable alterations in advanced cancer patients: a case series.
Drenner K, Basu GD, Goodman LJ, Ozols AA, LoBello JR, Royce T, Gordon MS, Borazanci EH, Steinbach MA, Trent J, Sharma S. Drenner K, et al. Among authors: gordon ms. Oncotarget. 2022 Oct 20;13:1174. doi: 10.18632/oncotarget.28294. Oncotarget. 2022. PMID: 36289011 Free PMC article. No abstract available.
Molecular profiling of melanoma brain metastases compared to primary cutaneous melanoma and to extracranial metastases.
In GK, Poorman K, Saul M, O'Day S, Farma JM, Olszanski AJ, Gordon MS, Thomas JS, Eisenberg B, Flaherty L, Weise A, Daveluy S, Gibney G, Atkins MB, Vanderwalde A. In GK, et al. Among authors: gordon ms. Oncotarget. 2020 Aug 18;11(33):3118-3128. doi: 10.18632/oncotarget.27686. eCollection 2020 Aug 18. Oncotarget. 2020. PMID: 32913556 Free PMC article.
Final outcomes analysis of the cell product SQZ-PBMC-HPV Phase 1 trial in incurable HPV16+ solid tumors shows improved overall survival in patients with increased CD8+ T cell tumor infiltration.
Weaver AN, Iams WT, Park JC, Mita M, Holtick U, Gordon MS, Rodabaugh KJ, Dhani N, Neupane P, Taylor M, Amanda Duvall E, Jennings J, Miselis NR, Loughhead S, Warren MS, Bernstein H, Klussmann JP, Baranda J, Jimeno A. Weaver AN, et al. Among authors: gordon ms. Mol Carcinog. 2024 May 2. doi: 10.1002/mc.23738. Online ahead of print. Mol Carcinog. 2024. PMID: 38695604
569 results