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Page 1
Identifying COPD subtypes using multi-trait genetics.
Ziyatdinov A, Hobbs BD, Kanaan-Izquierdo S, Moll M, Sakornsakolpat P, Shrine N, Chen J, Song K, Bowler RP, Castaldi PJ, Tobin MD, Kraft P, Silverman EK, Julienne H, Aschard H, Cho MH. Ziyatdinov A, et al. Among authors: aschard h. medRxiv [Preprint]. 2023 Feb 21:2023.02.20.23286186. doi: 10.1101/2023.02.20.23286186. medRxiv. 2023. PMID: 36865145 Free PMC article. Preprint.
Early IFNβ secretion determines variable downstream IL-12p70 responses upon TLR4 activation.
Posseme C, Llibre A, Charbit B, Bondet V, Rouilly V, Saint-André V, Boussier J, Bergstedt J, Smith N, Townsend L, Sugrue JA, Ní Cheallaigh C, Conlon N, Rotival M, Kobor MS, Mottez E, Pol S, Patin E, Albert ML, Quintana-Murci L, Duffy D; Milieu Intérieur Consortium. Posseme C, et al. Cell Rep. 2022 Jun 28;39(13):110989. doi: 10.1016/j.celrep.2022.110989. Cell Rep. 2022. PMID: 35767946 Free PMC article.
Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths.
Bastard P, Gervais A, Le Voyer T, Rosain J, Philippot Q, Manry J, Michailidis E, Hoffmann HH, Eto S, Garcia-Prat M, Bizien L, Parra-Martínez A, Yang R, Haljasmägi L, Migaud M, Särekannu K, Maslovskaja J, de Prost N, Tandjaoui-Lambiotte Y, Luyt CE, Amador-Borrero B, Gaudet A, Poissy J, Morel P, Richard P, Cognasse F, Troya J, Trouillet-Assant S, Belot A, Saker K, Garçon P, Rivière JG, Lagier JC, Gentile S, Rosen LB, Shaw E, Morio T, Tanaka J, Dalmau D, Tharaux PL, Sene D, Stepanian A, Megarbane B, Triantafyllia V, Fekkar A, Heath JR, Franco JL, Anaya JM, Solé-Violán J, Imberti L, Biondi A, Bonfanti P, Castagnoli R, Delmonte OM, Zhang Y, Snow AL, Holland SM, Biggs C, Moncada-Vélez M, Arias AA, Lorenzo L, Boucherit S, Coulibaly B, Anglicheau D, Planas AM, Haerynck F, Duvlis S, Nussbaum RL, Ozcelik T, Keles S, Bousfiha AA, El Bakkouri J, Ramirez-Santana C, Paul S, Pan-Hammarström Q, Hammarström L, Dupont A, Kurolap A, Metz CN, Aiuti A, Casari G, Lampasona V, Ciceri F, Barreiros LA, Dominguez-Garrido E, Vidigal M, Zatz M, van de Beek D, Sahanic S, Tancevski I, Stepanovskyy Y, Boyarchuk O, Nukui Y, Tsumura M, Vidaur L, Tangye SG, Burrel S, Duffy D, Quintana-Murci L, Klocperk A, Kann NY,… See abstract for full author list ➔ Bastard P, et al. Sci Immunol. 2021 Aug 19;6(62):eabl4340. doi: 10.1126/sciimmunol.abl4340. Sci Immunol. 2021. PMID: 34413139 Free PMC article.
Immune Profiling Enables Stratification of Patients With Active Tuberculosis Disease or Mycobacterium tuberculosis Infection.
Duffy D, Nemes E, Llibre A, Rouilly V, Musvosvi M, Smith N, Filander E, Africa H, Mabwe S, Jaxa L, Charbit B, Mulenga H, Tameris M, Walzl G, Malherbe S, Thomas S, Hatherill M, Bilek N, Scriba TJ, Albert ML; Milieu Intérieur Consortium. Duffy D, et al. Clin Infect Dis. 2021 Nov 2;73(9):e3398-e3408. doi: 10.1093/cid/ciaa1562. Clin Infect Dis. 2021. PMID: 33059361 Free PMC article.
Immune response profiling of patients with spondyloarthritis reveals signalling networks mediating TNF-blocker function in vivo.
Menegatti S, Guillemot V, Latis E, Yahia-Cherbal H, Mittermüller D, Rouilly V, Mascia E, Rosine N, Koturan S, Millot GA, Leloup C, Duffy D, Gleizes A, Hacein-Bey-Abina S; Milieu Intérieur Consortium; Sellam J, Berenbaum F, Miceli-Richard C, Dougados M, Bianchi E, Rogge L. Menegatti S, et al. Ann Rheum Dis. 2021 Apr;80(4):475-486. doi: 10.1136/annrheumdis-2020-218304. Epub 2020 Dec 2. Ann Rheum Dis. 2021. PMID: 33268443 Free PMC article.
The immune factors driving DNA methylation variation in human blood.
Bergstedt J, Azzou SAK, Tsuo K, Jaquaniello A, Urrutia A, Rotival M, Lin DTS, MacIsaac JL, Kobor MS, Albert ML, Duffy D, Patin E, Quintana-Murci L; Milieu Intérieur Consortium. Bergstedt J, et al. Nat Commun. 2022 Oct 6;13(1):5895. doi: 10.1038/s41467-022-33511-6. Nat Commun. 2022. PMID: 36202838 Free PMC article.
17q21 variants modify the association between early respiratory infections and asthma.
Smit LA, Bouzigon E, Pin I, Siroux V, Monier F, Aschard H, Bousquet J, Gormand F, Just J, Le Moual N, Nadif R, Scheinmann P, Vervloet D, Lathrop M, Demenais F, Kauffmann F; EGEA Cooperative Group. Smit LA, et al. Among authors: aschard h. Eur Respir J. 2010 Jul;36(1):57-64. doi: 10.1183/09031936.00154509. Epub 2009 Dec 23. Eur Respir J. 2010. PMID: 20032010 Free article.
Fitness cost of antibiotic susceptibility during bacterial infection.
Roux D, Danilchanka O, Guillard T, Cattoir V, Aschard H, Fu Y, Angoulvant F, Messika J, Ricard JD, Mekalanos JJ, Lory S, Pier GB, Skurnik D. Roux D, et al. Among authors: aschard h. Sci Transl Med. 2015 Jul 22;7(297):297ra114. doi: 10.1126/scitranslmed.aab1621. Sci Transl Med. 2015. PMID: 26203082
126 results