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Combined Treatment with a WNT Inhibitor and the NSAID Sulindac Reduces Colon Adenoma Burden in Mice with Truncated APC.
Faux MC, Weinstock J, Gogos S, Prato E, Azimpour AI, O'Keefe R, Cathcart-King Y, Garnham AL, Ernst M, Preaudet A, Christie M, Putoczki TL, Buchert M, Burgess AW. Faux MC, et al. Among authors: weinstock j. Cancer Res Commun. 2022 Feb 2;2(2):66-77. doi: 10.1158/2767-9764.CRC-21-0105. eCollection 2022 Feb. Cancer Res Commun. 2022. PMID: 36860494 Free PMC article.
Dual drug targeting to kill colon cancers.
Corona SP, Walker F, Weinstock J, Lessene G, Faux M, Burgess AW. Corona SP, et al. Among authors: weinstock j. Cancer Med. 2022 Jul;11(13):2612-2626. doi: 10.1002/cam4.4641. Epub 2022 Mar 17. Cancer Med. 2022. PMID: 35301819 Free PMC article.
Preclinical small molecule WEHI-7326 overcomes drug resistance and elicits response in patient-derived xenograft models of human treatment-refractory tumors.
Grohmann C, Walker F, Devlin M, Luo MX, Chüeh AC, Doherty J, Vaillant F, Ho GY, Wakefield MJ, Weeden CE, Kamili A, Murray J, Po'uha ST, Weinstock J, Kane SR, Faux MC, Broekhuizen E, Zheng Y, Shield-Artin K, Kershaw NJ, Tan CW, Witchard HM, Ebert G, Charman SA, Street I, Kavallaris M, Haber M, Fletcher JI, Asselin-Labat ML, Scott CL, Visvader JE, Lindeman GJ, Watson KG, Burgess AW, Lessene G. Grohmann C, et al. Among authors: weinstock j. Cell Death Dis. 2021 Mar 12;12(3):268. doi: 10.1038/s41419-020-03269-0. Cell Death Dis. 2021. PMID: 33712556 Free PMC article.
Colorectal Cancer Cell Line Proteomes Are Representative of Primary Tumors and Predict Drug Sensitivity.
Wang J, Mouradov D, Wang X, Jorissen RN, Chambers MC, Zimmerman LJ, Vasaikar S, Love CG, Li S, Lowes K, Leuchowius KJ, Jousset H, Weinstock J, Yau C, Mariadason J, Shi Z, Ban Y, Chen X, Coffey RJC, Slebos RJC, Burgess AW, Liebler DC, Zhang B, Sieber OM. Wang J, et al. Among authors: weinstock j. Gastroenterology. 2017 Oct;153(4):1082-1095. doi: 10.1053/j.gastro.2017.06.008. Epub 2017 Jun 16. Gastroenterology. 2017. PMID: 28625833 Free PMC article.
Antitumor efficacy of cytotoxic drugs and the monoclonal antibody 806 is enhanced by the EGF receptor inhibitor AG1478.
Johns TG, Luwor RB, Murone C, Walker F, Weinstock J, Vitali AA, Perera RM, Jungbluth AA, Stockert E, Old LJ, Nice EC, Burgess AW, Scott AM. Johns TG, et al. Among authors: weinstock j. Proc Natl Acad Sci U S A. 2003 Dec 23;100(26):15871-6. doi: 10.1073/pnas.2036503100. Epub 2003 Dec 15. Proc Natl Acad Sci U S A. 2003. PMID: 14676326 Free PMC article.
Preclinical analysis of the analinoquinazoline AG1478, a specific small molecule inhibitor of EGF receptor tyrosine kinase.
Ellis AG, Doherty MM, Walker F, Weinstock J, Nerrie M, Vitali A, Murphy R, Johns TG, Scott AM, Levitzki A, McLachlan G, Webster LK, Burgess AW, Nice EC. Ellis AG, et al. Among authors: weinstock j. Biochem Pharmacol. 2006 May 14;71(10):1422-34. doi: 10.1016/j.bcp.2006.01.020. Epub 2006 Mar 7. Biochem Pharmacol. 2006. PMID: 16522318
473 results