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Towards a multi-arm multi-stage platform trial of disease modifying approaches in Parkinson's disease.
Foltynie T, Gandhi S, Gonzalez-Robles C, Zeissler ML, Mills G, Barker R, Carpenter J, Schrag A, Schapira A, Bandmann O, Mullin S, Duffen J, McFarthing K, Chataway J, Parmar M, Carroll C; EJS ACT-PD Consortium. Foltynie T, et al. Among authors: chataway j. Brain. 2023 Jul 3;146(7):2717-2722. doi: 10.1093/brain/awad063. Brain. 2023. PMID: 36856727 Free PMC article.
Trials for neurodegenerative diseases: time to innovate.
Mehta AR, Chataway J, Pal S, Parmar MKB, Chandran S. Mehta AR, et al. Among authors: chataway j. Lancet Neurol. 2021 Dec;20(12):984. doi: 10.1016/S1474-4422(21)00388-4. Lancet Neurol. 2021. PMID: 34800413 Free PMC article. No abstract available.
Assessing Neurofilaments as Biomarkers of Neuroprotection in Progressive Multiple Sclerosis: From the MS-STAT Randomized Controlled Trial.
Williams TE, Holdsworth KP, Nicholas JM, Eshaghi A, Katsanouli T, Wellington H, Heslegrave A, Zetterberg H, Frost C, Chataway J. Williams TE, et al. Among authors: chataway j. Neurol Neuroimmunol Neuroinflamm. 2022 Jan 14;9(2):e1130. doi: 10.1212/NXI.0000000000001130. Print 2022 Mar. Neurol Neuroimmunol Neuroinflamm. 2022. PMID: 35031587 Free PMC article. Clinical Trial.
Motor Neuron Disease Systematic Multi-Arm Adaptive Randomised Trial (MND-SMART): a multi-arm, multi-stage, adaptive, platform, phase III randomised, double-blind, placebo-controlled trial of repurposed drugs in motor neuron disease.
Wong C, Dakin RS, Williamson J, Newton J, Steven M, Colville S, Stavrou M, Gregory JM, Elliott E, Mehta AR, Chataway J, Swingler RJ, Parker RA, Weir CJ, Stallard N, Parmar MKB, Macleod MR, Pal S, Chandran S. Wong C, et al. Among authors: chataway j. BMJ Open. 2022 Jul 7;12(7):e064173. doi: 10.1136/bmjopen-2022-064173. BMJ Open. 2022. PMID: 35798516 Free PMC article. Clinical Trial.
229 results