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Glucose-dependent insulinotropic polypeptide counteracts diet-induced obesity along with reduced feeding, elevated plasma leptin and activation of leptin-responsive and proopiomelanocortin neurons in the arcuate nucleus.
Han W, Wang L, Ohbayashi K, Takeuchi M, O'Farrell L, Coskun T, Rakhat Y, Yabe D, Iwasaki Y, Seino Y, Yada T. Han W, et al. Among authors: yada t. Diabetes Obes Metab. 2023 Jun;25(6):1534-1546. doi: 10.1111/dom.15001. Epub 2023 Feb 28. Diabetes Obes Metab. 2023. PMID: 36852745
Insulin Activates Vagal Afferent Neurons Including those Innervating Pancreas via Insulin Cascade and Ca(2+) Influx: Its Dysfunction in IRS2-KO Mice with Hyperphagic Obesity.
Iwasaki Y, Shimomura K, Kohno D, Dezaki K, Ayush EA, Nakabayashi H, Kubota N, Kadowaki T, Kakei M, Nakata M, Yada T. Iwasaki Y, et al. Among authors: yada t. PLoS One. 2013 Jun 26;8(6):e67198. doi: 10.1371/journal.pone.0067198. Print 2013. PLoS One. 2013. PMID: 23840624 Free PMC article.
Endogenous GLP-1 acts on paraventricular nucleus to suppress feeding: projection from nucleus tractus solitarius and activation of corticotropin-releasing hormone, nesfatin-1 and oxytocin neurons.
Katsurada K, Maejima Y, Nakata M, Kodaira M, Suyama S, Iwasaki Y, Kario K, Yada T. Katsurada K, et al. Among authors: yada t. Biochem Biophys Res Commun. 2014 Aug 22;451(2):276-81. doi: 10.1016/j.bbrc.2014.07.116. Epub 2014 Aug 1. Biochem Biophys Res Commun. 2014. PMID: 25089000
536 results