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Page 1
Proteomic Analysis of Mucosal and Systemic Responses to SARS-CoV-2 Antigen.
Martinson N, Gordhan B, Petkov S, Pillay AD, Seiphetlo T, Singh N, Otwombe K, Lebina L, Fredolini C, Chiodi F, Fox J, Kana B, Herrera C. Martinson N, et al. Among authors: seiphetlo t. Vaccines (Basel). 2023 Feb 2;11(2):334. doi: 10.3390/vaccines11020334. Vaccines (Basel). 2023. PMID: 36851212 Free PMC article.
Combined HIV Adolescent Prevention Study (CHAPS): comparison of HIV pre-exposure prophylaxis regimens for adolescents in sub-Saharan Africa-study protocol for a mixed-methods study including a randomised controlled trial.
Nash S, Dietrich J, Ssemata AS, Herrera C, O'Hagan K, Else L, Chiodi F, Kelly C, Shattock R, Chirenje M, Lebina L, Khoo S, Bekker LG, Weiss HA, Gray C, Stranix-Chibanda L, Kaleebu P, Seeley J, Martinson N, Fox J; CHAPS team. Nash S, et al. Trials. 2020 Oct 30;21(1):900. doi: 10.1186/s13063-020-04760-x. Trials. 2020. PMID: 33121503 Free PMC article.
Mobilization of systemic CCL4 following HIV pre-exposure prophylaxis in young men in Africa.
Petkov S, Herrera C, Else L, Mugaba S, Namubiru P, Odoch G, Opoka D, Pillay AAP, Seiphetlo TB, Serwanga J, Ssemata AS, Kaleebu P, Webb EL, Khoo S, Lebina L, Gray CM, Martinson N, Fox J, Chiodi F. Petkov S, et al. Among authors: seiphetlo tb. Front Immunol. 2022 Jul 27;13:965214. doi: 10.3389/fimmu.2022.965214. eCollection 2022. Front Immunol. 2022. PMID: 35967369 Free PMC article.
Short-term oral pre-exposure prophylaxis against HIV-1 modulates the transcriptome of foreskin tissue in young men in Africa.
Petkov S, Herrera C, Else L, Lebina L, Opoka D, Seiphetlo TB, Pillay AA, Mugaba S, Namubiru P, Odoch G, Ssemata AS, Serwanga J, Kaleebu P, Webb EL, Khoo S, Martinson N, Gray CM, Fox J, Chiodi F. Petkov S, et al. Among authors: seiphetlo tb. Front Immunol. 2022 Nov 18;13:1009978. doi: 10.3389/fimmu.2022.1009978. eCollection 2022. Front Immunol. 2022. PMID: 36479111 Free PMC article. Clinical Trial.
A randomized clinical trial of on-demand oral pre-exposure prophylaxis does not modulate lymphoid/myeloid HIV target cell density in the foreskin.
Rametse CL, Webb EL, Herrera C, Alinde B, Besethi A, Motaung B, Mbangiwa T, Leach L, Sebaa S, Pillay AAP, Seiphetlo TB, Malhangu B, Petkov S, Else L, Mugaba S, Namubiru P, Odoch G, Opoka D, Serwanga J, Ssemata AS, Kaleebu P, Khoo S, Lebina L, Martinson N, Chiodi F, Fox J, Gray CM; CHAPS consortium. Rametse CL, et al. Among authors: seiphetlo tb. AIDS. 2023 Sep 1;37(11):1651-1659. doi: 10.1097/QAD.0000000000003619. Epub 2023 Jun 6. AIDS. 2023. PMID: 37289572 Clinical Trial.
Dose finding study for on-demand HIV pre-exposure prophylaxis for insertive sex in sub-Saharan Africa: results from the CHAPS open label randomised controlled trial.
Herrera C, Serwanga J, Else L, Limakatso L, Opoka D, Ssemata AS, Pillay AD, Namubiru P, Seiphetlo TB, Odoch G, Mugaba S, Seatlholo P, Alieu A, Penchala SD, Muhumuza R, Alinde B, Petkov S, O'Hagan K, Callebaut C, Seeley J, Weiss H, Khoo S, Chiodi F, Gray CM, Kaleebu P, Webb EL, Martinson N, Fox J; CHAPS. Herrera C, et al. Among authors: seiphetlo tb. EBioMedicine. 2023 Jul;93:104648. doi: 10.1016/j.ebiom.2023.104648. Epub 2023 Jun 14. EBioMedicine. 2023. PMID: 37327677 Free PMC article. Clinical Trial.
Bacterial microbiome and host inflammatory gene expression in foreskin tissue.
Maust BS, Petkov S, Herrera C, Feng C, Brown BP, Lebina L, Opoka D, Ssemata A, Pillay N, Serwanga J, Seatlholo P, Namubiru P, Odoch G, Mugaba S, Seiphetlo T, Gray CM, Kaleebu P, Webb EL, Martinson N, Chiodi F, Fox J, Jaspan HB; CHAPS team. Maust BS, et al. Among authors: seiphetlo t. Heliyon. 2023 Nov 14;9(11):e22145. doi: 10.1016/j.heliyon.2023.e22145. eCollection 2023 Nov. Heliyon. 2023. PMID: 38053902 Free PMC article.
Evaluation of a human mucosal tissue explant model for SARS-CoV-2 replication.
Gordhan BG, Herrera C, Pillay AD, Seiphetlo T, Ealand CS, Machowski E, Singh N, Seatholo N, Otwombe K, Lebina L, Frise R, Scarlatti G, Chiodi F, Martinson N, Fox J, Kana BD. Gordhan BG, et al. Among authors: seiphetlo t. PLoS One. 2023 Sep 28;18(9):e0291146. doi: 10.1371/journal.pone.0291146. eCollection 2023. PLoS One. 2023. PMID: 37769001 Free PMC article.
SMA-TB: study protocol for the phase 2b randomized double-blind, placebo-controlled trial to estimate the potential efficacy and safety of two repurposed drugs, acetylsalicylic acid and ibuprofen, for use as adjunct therapy added to, and compared with, the standard WHO recommended TB regimen.
Arias L, Otwombe K, Waja Z, Tukvadze N, Korinteli T, Moloantoa T, Fonseca KL, Pillay N, Seiphetlo T, Ouchi-Vernet D, Siles A, Carabias L, Quiñones C, Vashakidze S, Martinson N, Vilaplana C. Arias L, et al. Among authors: seiphetlo t. Trials. 2023 Jun 28;24(1):435. doi: 10.1186/s13063-023-07448-0. Trials. 2023. PMID: 37370174 Free PMC article.