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Ratiometric Two-Photon Near-Infrared Probe to Detect DPP IV in Human Plasma, Living Cells, Human Tissues, and Whole Organisms Using Zebrafish.
Valverde-Pozo J, Paredes JM, Widmann TJ, Griñan-Lison C, Ceccarelli G, Gioiello A, Garcia-Rubiño ME, Marchal JA, Alvarez-Pez JM, Talavera EM. Valverde-Pozo J, et al. Among authors: gioiello a. ACS Sens. 2023 Mar 24;8(3):1064-1075. doi: 10.1021/acssensors.2c02025. Epub 2023 Feb 27. ACS Sens. 2023. PMID: 36847549 Free PMC article.
Nongenomic actions of bile acids. Synthesis and preliminary characterization of 23- and 6,23-alkyl-substituted bile acid derivatives as selective modulators for the G-protein coupled receptor TGR5.
Pellicciari R, Sato H, Gioiello A, Costantino G, Macchiarulo A, Sadeghpour BM, Giorgi G, Schoonjans K, Auwerx J. Pellicciari R, et al. Among authors: gioiello a. J Med Chem. 2007 Sep 6;50(18):4265-8. doi: 10.1021/jm070633p. Epub 2007 Aug 9. J Med Chem. 2007. PMID: 17685603
Bile acid derivatives as ligands of the farnesoid X receptor. Synthesis, evaluation, and structure-activity relationship of a series of body and side chain modified analogues of chenodeoxycholic acid.
Pellicciari R, Costantino G, Camaioni E, Sadeghpour BM, Entrena A, Willson TM, Fiorucci S, Clerici C, Gioiello A. Pellicciari R, et al. Among authors: gioiello a. J Med Chem. 2004 Aug 26;47(18):4559-69. doi: 10.1021/jm049904b. J Med Chem. 2004. PMID: 15317466
Progress and challenges of selective Farnesoid X Receptor modulation.
Massafra V, Pellicciari R, Gioiello A, van Mil SWC. Massafra V, et al. Among authors: gioiello a. Pharmacol Ther. 2018 Nov;191:162-177. doi: 10.1016/j.pharmthera.2018.06.009. Epub 2018 Jun 20. Pharmacol Ther. 2018. PMID: 29933033 Free article. Review.
Discovery of Multitarget Antivirals Acting on Both the Dengue Virus NS5-NS3 Interaction and the Host Src/Fyn Kinases.
Vincetti P, Caporuscio F, Kaptein S, Gioiello A, Mancino V, Suzuki Y, Yamamoto N, Crespan E, Lossani A, Maga G, Rastelli G, Castagnolo D, Neyts J, Leyssen P, Costantino G, Radi M. Vincetti P, et al. Among authors: gioiello a. J Med Chem. 2015 Jun 25;58(12):4964-75. doi: 10.1021/acs.jmedchem.5b00108. Epub 2015 Jun 15. J Med Chem. 2015. PMID: 26039671
Development of 3α,7α-dihydroxy-6α-ethyl-24-nor-5β-cholan-23-sulfate sodium salt (INT-767): Process optimization, synthesis and characterization of metabolites.
Cerra B, Venturoni F, Souma M, Ceccarelli G, Lozza AM, Passeri D, De Franco F, Baxendale IR, Pellicciari R, Macchiarulo A, Gioiello A. Cerra B, et al. Among authors: gioiello a. Eur J Med Chem. 2022 Nov 15;242:114652. doi: 10.1016/j.ejmech.2022.114652. Epub 2022 Aug 20. Eur J Med Chem. 2022. PMID: 36049273
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