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Fragment-based drug discovery of small molecule ligands for the human chemokine CCL28.
SLAS Discov. 2023 Jun;28(4):163-169. doi: 10.1016/j.slasd.2023.02.004. Epub 2023 Feb 23.
SLAS Discov. 2023.
PMID: 36841432
Free PMC article.
The non-ELR CXC chemokine encoded by human cytomegalovirus UL146 genotype 5 contains a C-terminal β-hairpin and induces neutrophil migration as a selective CXCR2 agonist.
Berg C, Wedemeyer MJ, Melynis M, Schlimgen RR, Hansen LH, Våbenø J, Peterson FC, Volkman BF, Rosenkilde MM, Lüttichau HR.
Berg C, et al. Among authors: schlimgen rr.
PLoS Pathog. 2022 Mar 10;18(3):e1010355. doi: 10.1371/journal.ppat.1010355. eCollection 2022 Mar.
PLoS Pathog. 2022.
PMID: 35271688
Free PMC article.
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Structural basis for selectivity and antagonism in extracellular GPCR-nanobodies.
Schlimgen RR, Peterson FC, Heukers R, Smit MJ, McCorvy JD, Volkman BF.
Schlimgen RR, et al.
Nat Commun. 2024 May 30;15(1):4611. doi: 10.1038/s41467-024-49000-x.
Nat Commun. 2024.
PMID: 38816420
Free PMC article.
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