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Antifungal Potential of Synthetic Peptides against Cryptococcus neoformans: Mechanism of Action Studies Reveal Synthetic Peptides Induce Membrane-Pore Formation, DNA Degradation, and Apoptosis.
Aguiar TKB, Neto NAS, Freitas CDT, Silva AFB, Bezerra LP, Malveira EA, Branco LAC, Mesquita FP, Goldman GH, Alencar LMR, Oliveira JTA, Santos-Oliveira R, Souza PFN. Aguiar TKB, et al. Among authors: oliveira jta. Pharmaceutics. 2022 Aug 12;14(8):1678. doi: 10.3390/pharmaceutics14081678. Pharmaceutics. 2022. PMID: 36015304 Free PMC article.
RcAlb-PepII, a synthetic small peptide bioinspired in the 2S albumin from the seed cake of Ricinus communis, is a potent antimicrobial agent against Klebsiella pneumoniae and Candida parapsilosis.
Dias LP, Souza PFN, Oliveira JTA, Vasconcelos IM, Araújo NMS, Tilburg MFV, Guedes MIF, Carneiro RF, Lopes JLS, Sousa DOB. Dias LP, et al. Among authors: oliveira jta. Biochim Biophys Acta Biomembr. 2020 Feb 1;1862(2):183092. doi: 10.1016/j.bbamem.2019.183092. Epub 2019 Oct 31. Biochim Biophys Acta Biomembr. 2020. PMID: 31678367 Free article.
Synthetic antimicrobial peptides: From choice of the best sequences to action mechanisms.
Souza PFN, Marques LSM, Oliveira JTA, Lima PG, Dias LP, Neto NAS, Lopes FES, Sousa JS, Silva AFB, Caneiro RF, Lopes JLS, Ramos MV, Freitas CDT. Souza PFN, et al. Among authors: oliveira jta. Biochimie. 2020 Aug;175:132-145. doi: 10.1016/j.biochi.2020.05.016. Epub 2020 Jun 11. Biochimie. 2020. PMID: 32534825 Free article.
Antidermatophytic activity of synthetic peptides: Action mechanisms and clinical application as adjuvants to enhance the activity and decrease the toxicity of Griseofulvin.
Souza PFN, Lima PG, Freitas CDT, Sousa DOB, Neto NAS, Dias LP, Vasconcelos IM, Freitas LBN, Silva RGG, Sousa JS, Silva AFB, Oliveira JTA. Souza PFN, et al. Among authors: oliveira jta. Mycoses. 2020 Sep;63(9):979-992. doi: 10.1111/myc.13138. Epub 2020 Aug 7. Mycoses. 2020. PMID: 32628303
A molecular docking study revealed that synthetic peptides induced conformational changes in the structure of SARS-CoV-2 spike glycoprotein, disrupting the interaction with human ACE2 receptor.
Souza PFN, Lopes FES, Amaral JL, Freitas CDT, Oliveira JTA. Souza PFN, et al. Among authors: oliveira jta. Int J Biol Macromol. 2020 Dec 1;164:66-76. doi: 10.1016/j.ijbiomac.2020.07.174. Epub 2020 Jul 18. Int J Biol Macromol. 2020. PMID: 32693122 Free PMC article.
103 results