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Combining X-ray crystallography and molecular modeling toward the optimization of pyrazolo[3,4-d]pyrimidines as potent c-Src inhibitors active in vivo against neuroblastoma.
Tintori C, Fallacara AL, Radi M, Zamperini C, Dreassi E, Crespan E, Maga G, Schenone S, Musumeci F, Brullo C, Richters A, Gasparrini F, Angelucci A, Festuccia C, Delle Monache S, Rauh D, Botta M. Tintori C, et al. Among authors: brullo c. J Med Chem. 2015 Jan 8;58(1):347-61. doi: 10.1021/jm5013159. Epub 2014 Dec 3. J Med Chem. 2015. PMID: 25469771
Pyrrolo[2,3-d]Pyrimidines as Kinase Inhibitors.
Musumeci F, Sanna M, Grossi G, Brullo C, Fallacara AL, Schenone S. Musumeci F, et al. Among authors: brullo c. Curr Med Chem. 2017;24(19):2059-2085. doi: 10.2174/0929867324666170303162100. Curr Med Chem. 2017. PMID: 28266267 Review.
Synthesis and biological evaluation of N-pyrazolyl-N'-alkyl/benzyl/phenylureas: a new class of potent inhibitors of interleukin 8-induced neutrophil chemotaxis.
Bruno O, Brullo C, Bondavalli F, Schenone S, Ranise A, Arduino N, Bertolotto MB, Montecucco F, Ottonello L, Dallegri F, Tognolini M, Ballabeni V, Bertoni S, Barocelli E. Bruno O, et al. Among authors: brullo c. J Med Chem. 2007 Jul 26;50(15):3618-26. doi: 10.1021/jm0704402. Epub 2007 Jul 4. J Med Chem. 2007. PMID: 17608466
111 results