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The monocyte cell surface is a unique site of autoantigen generation in rheumatoid arthritis.
Thomas MA, Naik P, Wang H, Giles JT, Girgis AA, Kim SY, Johnson TP, Curran AM, Crawford JD, Jahanbani S, Bingham CO, Robinson WH, Na CH, Darrah E. Thomas MA, et al. Among authors: girgis aa. Proc Natl Acad Sci U S A. 2024 Apr 23;121(17):e2304199121. doi: 10.1073/pnas.2304199121. Epub 2024 Apr 17. Proc Natl Acad Sci U S A. 2024. PMID: 38630712
The XIST lncRNA is a sex-specific reservoir of TLR7 ligands in SLE.
Crawford JD, Wang H, Trejo-Zambrano D, Cimbro R, Talbot CC Jr, Thomas MA, Curran AM, Girgis AA, Schroeder JT, Fava A, Goldman DW, Petri M, Rosen A, Antiochos B, Darrah E. Crawford JD, et al. Among authors: girgis aa. JCI Insight. 2023 Sep 21;8(20):e169344. doi: 10.1172/jci.insight.169344. JCI Insight. 2023. PMID: 37733447 Free PMC article.
Pancreatic cancer is marked by complement-high blood monocytes and tumor-associated macrophages.
Kemp SB, Steele NG, Carpenter ES, Donahue KL, Bushnell GG, Morris AH, The S, Orbach SM, Sirihorachai VR, Nwosu ZC, Espinoza C, Lima F, Brown K, Girgis AA, Gunchick V, Zhang Y, Lyssiotis CA, Frankel TL, Bednar F, Rao A, Sahai V, Shea LD, Crawford HC, Pasca di Magliano M. Kemp SB, et al. Among authors: girgis aa. Life Sci Alliance. 2021 Mar 29;4(6):e202000935. doi: 10.26508/lsa.202000935. Print 2021 Jun. Life Sci Alliance. 2021. PMID: 33782087 Free PMC article.