Bonomo RA - Search Results

1

Gating interactions steer loop conformational changes in the active site of the L1 metallo-β-lactamase.

Zhao Z, Shen X, Chen S, Gu J, Wang H, Mojica MF, Samanta M, Bhowmik D, Vila AJ, Bonomo RA, Haider S. Zhao Z, et al. Among authors: bonomo ra. Elife. 2023 Feb 24;12:e83928. doi: 10.7554/eLife.83928. Elife. 2023. PMID: 36826989 Free PMC article.

2

Complementary roles of mutations at positions 69 and 242 in a class A beta-lactamase.

Bonomo RA, Dawes CG, Knox JR, Shlaes DM. Bonomo RA, et al. Biochim Biophys Acta. 1995 Feb 22;1247(1):113-20. doi: 10.1016/0167-4838(94)00187-l. Biochim Biophys Acta. 1995. PMID: 7873579

3

beta-Lactamase mutations far from the active site influence inhibitor binding.

Bonomo RA, Dawes CG, Knox JR, Shlaes DM. Bonomo RA, et al. Biochim Biophys Acta. 1995 Feb 22;1247(1):121-5. doi: 10.1016/0167-4838(94)00188-m. Biochim Biophys Acta. 1995. PMID: 7873581

4

High resolution crystal structures of the trans-enamine intermediates formed by sulbactam and clavulanic acid and E166A SHV-1 {beta}-lactamase.

Padayatti PS, Helfand MS, Totir MA, Carey MP, Carey PR, Bonomo RA, van den Akker F. Padayatti PS, et al. Among authors: bonomo ra. J Biol Chem. 2005 Oct 14;280(41):34900-7. doi: 10.1074/jbc.M505333200. Epub 2005 Jul 29. J Biol Chem. 2005. PMID: 16055923 Free article.

5

Inhibition of OXA-1 beta-lactamase by penems.

Bethel CR, Distler AM, Ruszczycky MW, Carey MP, Carey PR, Hujer AM, Taracila M, Helfand MS, Thomson JM, Kalp M, Anderson VE, Leonard DA, Hujer KM, Abe T, Venkatesan AM, Mansour TS, Bonomo RA. Bethel CR, et al. Among authors: bonomo ra. Antimicrob Agents Chemother. 2008 Sep;52(9):3135-43. doi: 10.1128/AAC.01677-07. Epub 2008 Jun 16. Antimicrob Agents Chemother. 2008. PMID: 18559643 Free PMC article.

6

Inhibitor resistance in the KPC-2 beta-lactamase, a preeminent property of this class A beta-lactamase.

Papp-Wallace KM, Bethel CR, Distler AM, Kasuboski C, Taracila M, Bonomo RA. Papp-Wallace KM, et al. Among authors: bonomo ra. Antimicrob Agents Chemother. 2010 Feb;54(2):890-7. doi: 10.1128/AAC.00693-09. Epub 2009 Dec 14. Antimicrob Agents Chemother. 2010. PMID: 20008772 Free PMC article.

7

Three decades of beta-lactamase inhibitors.

Drawz SM, Bonomo RA. Drawz SM, et al. Among authors: bonomo ra. Clin Microbiol Rev. 2010 Jan;23(1):160-201. doi: 10.1128/CMR.00037-09. Clin Microbiol Rev. 2010. PMID: 20065329 Free PMC article. Review.

8

Penicillin sulfone inhibitors of class D beta-lactamases.

Drawz SM, Bethel CR, Doppalapudi VR, Sheri A, Pagadala SR, Hujer AM, Skalweit MJ, Anderson VE, Chen SG, Buynak JD, Bonomo RA. Drawz SM, et al. Among authors: bonomo ra. Antimicrob Agents Chemother. 2010 Apr;54(4):1414-24. doi: 10.1128/AAC.00743-09. Epub 2010 Jan 19. Antimicrob Agents Chemother. 2010. PMID: 20086146 Free PMC article.

9

Elucidating the role of Trp105 in the KPC-2 β-lactamase.

Papp-Wallace KM, Taracila M, Wallace CJ, Hujer KM, Bethel CR, Hornick JM, Bonomo RA. Papp-Wallace KM, et al. Among authors: bonomo ra. Protein Sci. 2010 Sep;19(9):1714-27. doi: 10.1002/pro.454. Protein Sci. 2010. PMID: 20662006 Free PMC article.

10

Ligand-dependent disorder of the Omega loop observed in extended-spectrum SHV-type beta-lactamase.

Sampson JM, Ke W, Bethel CR, Pagadala SR, Nottingham MD, Bonomo RA, Buynak JD, van den Akker F. Sampson JM, et al. Among authors: bonomo ra. Antimicrob Agents Chemother. 2011 May;55(5):2303-9. doi: 10.1128/AAC.01360-10. Epub 2011 Feb 28. Antimicrob Agents Chemother. 2011. PMID: 21357298 Free PMC article.

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