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Multiple sclerosis patient-derived spontaneous B cells have distinct EBV and host gene expression profiles in active disease.
Soldan SS, Su C, Monaco MC, Yoon L, Kannan T, Zankharia U, Patel RJ, Dheekollu J, Vladimirova O, Dowling JW, Thebault S, Brown N, Clauze A, Andrada F, Feder A, Planet PJ, Kossenkov A, Schäffer DE, Ohayon J, Auslander N, Jacobson S, Lieberman PM. Soldan SS, et al. Among authors: kossenkov a. Nat Microbiol. 2024 May 28. doi: 10.1038/s41564-024-01699-6. Online ahead of print. Nat Microbiol. 2024. PMID: 38806670
Targeting LxCxE cleft pocket of retinoblastoma protein in M2 macrophages inhibits ovarian cancer progression.
Tcyganov EN, Kwak T, Yang X, Poli ANR, Hart C, Bhuniya A, Cassel J, Kossenkov A, Auslander N, Lu L, Sharma P, Mendoza MGC, Zhigarev D, Cadungog MG, Jean S, Chatterjee-Paer S, Weiner D, Donthireddy L, Bristow B, Zhang R, Tyurin VA, Tyurina YY, Bayir H, Kagan VE, Salvino JM, Montaner LJ. Tcyganov EN, et al. Among authors: kossenkov a. bioRxiv [Preprint]. 2024 May 14:2024.05.10.593562. doi: 10.1101/2024.05.10.593562. bioRxiv. 2024. PMID: 38798466 Free PMC article. Preprint.
Immunoglobulin G N-glycan markers of accelerated biological aging during chronic HIV infection.
Giron LB, Liu Q, Adeniji OS, Yin X, Kannan T, Ding J, Lu DY, Langan S, Zhang J, Azevedo JLLC, Li SH, Shalygin S, Azadi P, Hanna DB, Ofotokun I, Lazar J, Fischl MA, Haberlen S, Macatangay B, Adimora AA, Jamieson BD, Rinaldo C, Merenstein D, Roan NR, Kutsch O, Gange S, Wolinsky SM, Witt MD, Post WS, Kossenkov A, Landay AL, Frank I, Tien PC, Gross R, Brown TT, Abdel-Mohsen M. Giron LB, et al. Among authors: kossenkov a. Nat Commun. 2024 Apr 10;15(1):3035. doi: 10.1038/s41467-024-47279-4. Nat Commun. 2024. PMID: 38600088 Free PMC article.
Cell state dependent effects of Bmal1 on melanoma immunity and tumorigenicity.
Zhang X, Pant SM, Ritch CC, Tang HY, Shao H, Dweep H, Gong YY, Brooks R, Brafford P, Wolpaw AJ, Lee Y, Weeraratna A, Sehgal A, Herlyn M, Kossenkov A, Speicher D, Sorger PK, Santagata S, Dang CV. Zhang X, et al. Among authors: kossenkov a. Nat Commun. 2024 Jan 20;15(1):633. doi: 10.1038/s41467-024-44778-2. Nat Commun. 2024. PMID: 38245503 Free PMC article.
A cyclin D1 intrinsically disordered domain accesses modified histone motifs to govern gene transcription.
Jiao X, Di Sante G, Casimiro MC, Tantos A, Ashton AW, Li Z, Quach Y, Bhargava D, Di Rocco A, Pupo C, Crosariol M, Lazar T, Tompa P, Wang C, Yu Z, Zhang Z, Aldaaysi K, Vadlamudi R, Mann M, Skordalakes E, Kossenkov A, Du Y, Pestell RG. Jiao X, et al. Among authors: kossenkov a. Oncogenesis. 2024 Jan 8;13(1):4. doi: 10.1038/s41389-023-00502-1. Oncogenesis. 2024. PMID: 38191593 Free PMC article.
Acetate acts as a metabolic immunomodulator by bolstering T-cell effector function and potentiating antitumor immunity in breast cancer.
Miller KD, O'Connor S, Pniewski KA, Kannan T, Acosta R, Mirji G, Papp S, Hulse M, Mukha D, Hlavaty SI, Salcido KN, Bertolazzi F, Srikanth YVV, Zhao S, Wellen KE, Shinde RS, Claiborne DT, Kossenkov A, Salvino JM, Schug ZT. Miller KD, et al. Among authors: kossenkov a. Nat Cancer. 2023 Oct;4(10):1491-1507. doi: 10.1038/s43018-023-00636-6. Epub 2023 Sep 18. Nat Cancer. 2023. PMID: 37723305
232 results