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ELAVL4, splicing, and glutamatergic dysfunction precede neuron loss in MAPT mutation cerebral organoids.
Bowles KR, Silva MC, Whitney K, Bertucci T, Berlind JE, Lai JD, Garza JC, Boles NC, Mahali S, Strang KH, Marsh JA, Chen C, Pugh DA, Liu Y, Gordon RE, Goderie SK, Chowdhury R, Lotz S, Lane K, Crary JF, Haggarty SJ, Karch CM, Ichida JK, Goate AM, Temple S. Bowles KR, et al. Among authors: liu y. Cell. 2021 Aug 19;184(17):4547-4563.e17. doi: 10.1016/j.cell.2021.07.003. Epub 2021 Jul 26. Cell. 2021. PMID: 34314701 Free PMC article.
17q21.31 sub-haplotypes underlying H1-associated risk for Parkinson's disease are associated with LRRC37A/2 expression in astrocytes.
Bowles KR, Pugh DA, Liu Y, Patel T, Renton AE, Bandres-Ciga S, Gan-Or Z, Heutink P, Siitonen A, Bertelsen S, Cherry JD, Karch CM, Frucht SJ, Kopell BH, Peter I, Park YJ; International Parkinson’s Disease Genomics Consortium (IPDGC); Charney A, Raj T, Crary JF, Goate AM. Bowles KR, et al. Among authors: liu y. Mol Neurodegener. 2022 Jul 15;17(1):48. doi: 10.1186/s13024-022-00551-x. Mol Neurodegener. 2022. PMID: 35841044 Free PMC article.
Upregulated GIRK2 counteracts ethanol-induced changes in excitability & respiration in human neurons.
Prytkova I, Liu Y, Fernando M, Gameiro-Ros I, Popova D, Kamarajan C, Xuei X, Chorlian DB, Edenberg HJ, Tischfield JA, Porjesz B, Pang ZP, Hart RP, Goate A, Slesinger PA. Prytkova I, et al. Among authors: liu y. bioRxiv [Preprint]. 2024 Jan 13:2023.03.22.533236. doi: 10.1101/2023.03.22.533236. bioRxiv. 2024. PMID: 36993693 Free PMC article. Updated. Preprint.
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